Revive Therapeutics Ltd C.RVV

Poor trial design, terrible sites, pitiful management

[1ottrunner]

Which is obvious from todays update.  The trial hasn't even reach 600 patients yet!

[RandomGuy1]

Please stop.  

[1ottrunner]

Stop what?  Offering the truth? Trial completion will be updated to end of Q4 at the earliest.

[RandomGuy1]

Just trolling a bit.  But what's your honest opinion on this?  Is this considered good news for us hoping or is it lacklustre?  Does this imply that they have been performing the trials and thus far, no serious side effects have occurred?  How do you interpret this? To date, the ongoing Study has not seen any serious adverse events or safety concerns that required the

[1ottrunner]

The best news is that they have decided on a dose. That means the DSMB reviewed initial data and made that decision. Good news is they could have reviewed it and decided not to continue.  It must mean that the higher dose has efficacy beyond the placebo and lower dose. What we need as investors is real recruitment!  With 40 sites this trial should be fully rectruited in 30 days. M

[Towser7]

Fantastic summary.   I really want to know why the recruitment is such an issue.  There's been no comment on that fro MF.  Can't they provide incentives?  The cost would be minimal compared to the potential revenue they will miss out on by continued slow progress.

[captainbrouwer]

For a good discussion about trial/update/dosage etc see the live chat on rvvtf subreddit, especially between biomedicaltrader, dalesreport and nostatistician. Ignore 1ottrunner, he's an idiot

[1ottrunner]

Yes the reddit gang, I'm sure they are all very intelligent.  This trial has been running 2 weeks short of a year. You heard it here, 50 weeks.  The trial design has finally enrolled 50% participation. None of the trial sites offer any information regarding this trial, they list others, but not this. So captainbrouwer, how great is this trial designed? You want to know a good

[captainbrouwer]

As usual you don't know what you're talking about dummy

[90guppy]

yep, as usual paid hacks, get paid to bash, must be miserable to do what paid hacks do, aint got dough to make any bet, but bash for pennies