Liminal BioSciences Inc. LMNL

Patent update

[PLIImfoservice]

Patents Assigned to LIMINAL BIOSCIENCES LIMITED

• Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of osteoporosis

  Patent number: 11185521

  Abstract: The present invention concerns the use of compounds for preventing and/or treating osteoporosis, for stimulating bone formation, for stimulating bone remodeling, for stimulating the differentiation and mineralization of osteoblasts, for inhibiting bone resorption and for modulating serum level of adiponectin in a subject. These uses have been found for compounds represented by Formula I and pharmaceutically acceptable salts thereof, wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R1 is H, F or OH; R2 is H, F, OH, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R3 is H, F, OH or CH2Ph; R4 is H, F, or OH; Q is 1) (CH2)mC(O)OH wherein m is 1 or 2, 2) CH(F)—C(O)OH, 3) CF2—C(O)OH, or 4) C(O)—C(O)OH.

  Type: Grant

  Filed: April 9, 2020

  Date of Patent: November 30, 2021

  Assignee: LIMINAL BIOSCIENCES LIMITED

  Inventors: Lyne Gagnon, Brigitte Grouix

• Phenylketone carboxylate compounds and pharmaceutical compositions for the prevention and treatment of osteoporosis

  Patent number: 10925846

  Abstract: The present invention concerns the use of compounds for preventing and/or treating osteoporosis, for stimulating bone formation, for stimulating the differentiation and mineralization of osteoblasts, or for inhibiting bone resorption in a subject. These novel uses have been found for compounds represented by Formula I and pharmaceutically acceptable salts thereof. wherein: R1 and R2 are independently equal to H, F or OH; A is (CH2)mCOOH, W(CH2)mCOOH, or Y—CH(COOH)—(CH2)p-CH3 when B is H; or B is (CH2)mCOOH, W(CH2)mCOOH, or Y—CH(COOH)—(CH2)p—CH3 when A is H; or A and B are covalently bonded to form a five (5), six (6), or seven (7)-membered cycloalkyl substituted with COOH; where: Y is O, S, HN or CH2; W is 0, S or NH; m is 0-2; and p is 3-7; D is CO(CH2)nCH3 or CHOH(CH2)nCH3 or O(CH2)nCH3 where n is 2-6; and E is H or F.

  Type: Grant

  Filed: October 8, 2015

  Date of Patent: February 23, 2021

  Assignee: LIMINAL BIOSCIENCES LIMITED

  Inventors: Lyne Gagnon, Brigitte Grouix

• Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration

  Patent number: 10869849

  Abstract: Described herein are compounds of Formula I, or pharmaceutically acceptable salts thereof, or combinations thereof, as well as uses thereof. Such uses include promoting tissue self-repair or tissue regeneration of an organ, stimulating the generation of tissue growth, modulating (e.g., increasing) the level of a tissue-repair marker, treating physical injury in an organ, tissue or cell, promoting wound healing, as well as anti-aging applications. Corresponding compositions, methods, kits, and uses are also described. Formula I wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R1 is H, F of OH; R2 is H, F, OH, C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(O)—(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R3 is H, F, OH, or CH2Ph; R4 is H, F or OH; Q is 1) (CH2), C(O)OH wherein m is 1 or 2 2) CH(CH3)C(O)OH, 3) C(CH3)2C(O)OH, 4) CH(F)—C(O)OH, 5) CF2—C(O)OH or 6) C(O)—C(O)OH.

  Type: Grant

  Filed: July 12, 2019

  Date of Patent: December 22, 2020

  Assignee: LIMINAL BIOSCIENCES LIMITED

  Inventors: Lyne Gagnon, Pierre Laurin

[37minus4]

The return of the White Wine Barney Fife (skyhigh): good or bad omen? Discuss. ;-) 33

[Dibah420]

Divertissement gratuit ..

[PLIImfoservice]

Just checking to see if this stock is still alive 

[stockbuphoon]

Management and Thomvest are doing everything they can to get it delisted. It's an easily telegraphed plan. Thomvest knew the offers on table in 2018 and they pulled off the financial engineering to take over the company in 2019. Now, they are burying anything of perceived value in company such as 4050.   

[PLIImfoservice]

Those kcoc srekcus have to be dealt with imho 

[37minus4]

^^^^ And there is the answer ^^^^ :-P 33