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Bullboard - Stock Discussion Forum
Palisade Bio Inc
PALI
Healthcare
Biotechnology
Palisade Bio, Inc. is a biopharmaceutical company focused on developing novel therapeutics for serious chronic gastrointestinal diseases. It is engaged in advancing a PALI-2108 for the treatment of IBD, including UC and CD and are researching PALI-1908. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract. UC primarily affects the colon and the rectum. CD...
can affect any part of the gastrointestinal tract, from the mouth to the anus. PALI-2108 is a prodrug PDE4 inhibitor that operates through a mechanism within colon tissues, targeting the key enzyme phosphodiesterase-4 (PDE4). This enzyme is pivotal in cAMP hydrolysis, and by inhibiting PDE4, intracellular cAMP levels are elevated. This elevation leads to the downregulation of inflammatory cytokines and a reduction in the expression of cell adhesion molecules. By modulating these processes, PALI-2108 prevents the local infiltration and activation of inflammatory cells in the colon tissues.
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NDAQ:PALI - Post Discussion
Palisade Bio Inc
> PALI ..... on the run
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•••
Iseneschal
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Post by
Iseneschal
on Aug 31, 2021 10:18am
PALI ..... on the run
Cheers !
(72)
•••
Iseneschal
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Comment by
Iseneschal
on Aug 31, 2021 11:47am
The "run" didn't last long....as usual.....hehe No news....therefore not "Primetime"....jmho I will be buying "the dip"..... not advice. Cheers !
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