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Bullboard - Stock Discussion Forum ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational... see more

NDAQ:PMN - Post Discussion

ProMIS Neurosciences Inc > Kaplan's poster
View:
Post by M101 on Aug 04, 2021 1:48pm

Kaplan's poster

This was news to me, so maybe to other investors as well. It seems far more important to Promis that it would be to most of our competition, and so deserving of more promotional attention.

"Small misfolded regions (conformational epitopes) exposed on misfolded toxic A-syn, tau and Ab are sufficient to replicate the seeding activity of the full-length protein suggesting that they directly contribute to prion-like pathogenicity "
Comment by DavidKingCanada on Aug 04, 2021 2:54pm
Great find and really interesting. I never knew I would enjoy reading about Neurodegenerative Diseases until I started Investing in PMN. I do believe there will be lots of exciting news in the future not only from PMN but also from our Competitors. 
Comment by SouthernTierTom on Aug 04, 2021 8:09pm
I've never seen a company that are such good "corporate sports"  They applaud all the advancements of companies actually doing something and have posters that think likewise.  Really, an admirable form of corporate conduct.  The market cap is inching up again too, darn near worth 70M CAD.  Are we expecting news from one of their phase 2 or phase 3 trials in the ...more  
Comment by Thenorth1990 on Aug 04, 2021 11:37pm
Absolutely , that's the sole purpose of our Pr team.
Comment by M101 on Aug 06, 2021 2:53pm
I guess I shouldn't be surprised that no one here had a constructive comment, it's complicated if not esoteric. If Gene's update can be believed then this is novel, i.e. it's not the same as propagation by templating the whole misfolded protein. So does this mean the epitope itself can spread the disease, or would it be just minor contributor?  templating backgrounder: https ...more  
Comment by Thenorth1990 on Aug 06, 2021 3:53pm
Mainly coz it science is difficult and it's much easy to invest in a science based company and bash the management . Sorry bud , I wish I had a better grasp
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