Join today and have your say! It’s FREE!

Become a member today, It's free!

We will not release or resell your information to third parties without your permission.
Please Try Again
{{ error }}
By providing my email, I consent to receiving investment related electronic messages from Stockhouse.

or

Sign In

Please Try Again
{{ error }}
Password Hint : {{passwordHint}}
Forgot Password?

or

Please Try Again {{ error }}

Send my password

SUCCESS
An email was sent with password retrieval instructions. Please go to the link in the email message to retrieve your password.

Become a member today, It's free!

We will not release or resell your information to third parties without your permission.
Quote  |  Bullboard  |  News  |  Opinion  |  Profile  |  Peers  |  Filings  |  Financials  |  Options  |  Price History  |  Ratios  |  Ownership  |  Insiders  |  Valuation

Bullboard - Stock Discussion Forum ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational... see more

NDAQ:PMN - Post Discussion

ProMIS Neurosciences Inc > The Bleeding continues
View:
Post by retiredcop on Nov 28, 2022 8:15am

The Bleeding continues

https://www.science.org/content/article/second-death-linked-potential-antibody-treatment-alzheimer-s-disease

Just a day before they are suppposed to present their data at the clinical trials conference , another potential death that could be attributed to brain bleeding, this time the severe reaction with a anti-clotting medicine.  
I am sure this is going to be on everyones mind and it will be very very interesting to see the questions and comments /opinions of experts after this presentation. Big question " will it impact how the FDA  looks at the fast track approval for this porduct "  
If you examine this report , that same thing jumps out at you " this company is trying to remove the amyloid plaque from the brain" 
This could have a very positive outlook for  companies like PMN that are dealing with the misfolded oligomer and ignoring the plaque as the main culprit in AD.
Comment by bball67 on Nov 28, 2022 10:08am
A second death from Lecanemab is significant but it might take one or two more deaths before things start to fall apart. Lower dosages to reduce this risk lowers any potential benefits. More deaths will possibly affect approval prospects. Even if approved,  doctors and neurologists will be loathe to recommend that a patient use the product from a liability standpoint. PMN 310 is different in ...more  
Comment by M101 on Nov 28, 2022 11:38am
Big thumbs up for this post RC. This why the aducanumab bandwagon strategy was always destined to fail, why we always should have had a strategy of strong differentiation along with modest respect, and therefore why Gene and Elliot had to be removed.  And why we as minor shareholders have to remain wary of management with divided loyalties.