Spectral Medical Inc T.EDT

More proof on extended duration of PMX-DHP !

[mercedesman]

https://read.qxmd.com/read/33910191/impact-of-extended-duration-of-polymyxin-b-immobilized-fiber-column-direct-hemoperfusion-on-hemodynamics-vasoactive-substance-requirement-and-pulmonary-oxygenation-in-patients-with-sepsis-an-observational-study


"DISCUSSION/CONCLUSIONS: Longer duration of PMX-DHP was associated with the improved MAP and decreased volume of vasoactive-inotropic agents compared with the conventional duration. Eight and longer hours duration of PMX-DHP was associated with the improvement in the pulmonary oxygenation. Further studies are needed to confirm the efficacy of longer duration of PMX-DHP in patients with septic shock."

Three points:

Who knew that by removing more endotoxins (perhaps until the infection sourse has been adequantely controlled) would improve outcomes?

Wonder how the FDA will deal with this complelling new real world evidence as they finalize their reiew of Tigris results?

Would using more filters or higher capacity filters increase the long term revenues of Spectral assuming FDA approva?  Hmmmm?!

MM

[inspecthrgadget]

I am expecting a similar result from the ongoing Covid study in the US. There, it the potential of additional filter use that could expand on the "dose response" relationship that Spilker et al recognized in the phase 3 trial. We are ALL learning as we proceed, perhsps more important was the recognition of the PMX filters capacity, perhaps the trial's biggest learn as wr do have a

[Domino55]

MM- this BB has how many regular posters? 3, 4 maybe. it just occurred to me that they have more North American regulatory approvals than they do people posting and discussing them on Stockhouse. how many micro caps can say that?!

[mercedesman]

lol.  Quite right Although it may be more correct to say 3 - 4 vocal posters, or posters of value. typical number of reads range between 70 and 200, depending on the topic. Would be nice to hear from a few of silent majority, once in a while. If they are all  weak incarnations of  a few bad guys, I'm not sure why St and his various alias' would go to the trouble of 

[mercedesman]

Wow !!!!???!!! That seems like very good news doesn't  it MM?  (resist the temptation Davi - lately you're coming around lol) If you place the following key puzzle peices, doesn't it make you feel better about your investment, despite Mgt's silence and or modest behaviour? Kellum takes a two year leave from UoP to become CMO of Spectral Kellum acquires a