Spectral Medical Inc T.EDT

Spectral on Linkedin Today

[TechOne]

Understanding Endotoxin Detection: EAA™ vs. LAL Assay

The Endotoxin Activity Assay (EAA™) and the Limulus Amebocyte Lysate (LAL) assay are two prominent methods for detecting endotoxins, but their methodologies and applications vary significantly. Here's a breakdown:

Methodology

• EAA™: Measures neutrophil activation, rapidly assessing endotoxin levels in whole blood.
• LAL Assay: Utilizes lysate from horseshoe crab blood, detecting endotoxin through coagulation reactions.

Sensitivity and Specificity

• EAA™: Optimized for low endotoxin concentrations, effective in clinical scenarios, and has been correlated with patient outcomes.
• LAL Assay: a quantitative test for endotoxin measurement in crystalloid solutions, but cannot accurately detect endotoxin in whole blood or plasma.

In summary:

• The EAA™ is ideal for semi-quantitative analysis of endotoxins in whole blood, suitable for clinical use.
• The LAL Assay is best for precise endotoxin detection in crystalloid solutions but not appropriate for blood-based samples.

Understanding these differences can help in choosing the right assay for specific research or clinical applications. Learn more: https://buff.ly/3ZyGoYJ

[PezDalatoYou]

I find it interesting that Spectral continues to post in a positive manner on LinkedIn. Given that they already know the direction of the trial outcome, I think it would be a fraud to continue to publicly post this stuff if the trial is headed in a negative direction. Although my trust in the management team doesn't totally dismiss a fraud, an intentional and obvious fraud would be unlikely, I

[Geery]

Pez, I am with you on both parts of your comment. Positive posts feel good, but like you, in my many years of Spectral share ownership I have never had any trust in mgmt.  Maybe I missed something over the years but I can't think of any moments/updates/anniuncements/etc., that made me think different.  Is this the norm for tiny cap companies going through these trials? 

[Spamme54321]

You are right not to trust management. All company management are self serving. They dont care about the shareholders just like we dont care about them. We are all here to make a profit.

[gebremeskel]

When a company is in the last stages of its' existence and the company's managers have built up substantial personal share counts in anticipation of the endgame, how do the interests of managers diverge from the interests of any other shareholders?

[mercedesman]

Hey G  You're are correct... the interests of Mgt. and minority shareholders are almost  and finally fully aligned.  Perhaps after one more final option/ PSU/ DS/U warrant /etc grant they will be 100% aligned ?  The ball is in CG's court, at least on the first issue of taking ownership of Vantive which has to be weeks, or worst case, down to a month or so away

[Spamme54321]

I am just saying if they could find a way to screw over the shareholders to make a quick buck for themselves 100% they would do it. Not saying we currently don't have the same goals.

[oilandgasman]

My problem with management is they’ve thought they were holding aces a few times and flipped 2’s when called.   The pump and October 2016 result disappointment still ring here. 

[hmmmmmmmm]

Interesting. I'm not on LikedIn but curious- are they posting statements re: the Tigris trial? Most of their posts that have been reposted here have been EAA related. If they are making "exceeding expec†ation" esq claims on LikedIn that would be telling..

[BlueJays9293]

Didn't 60 Minutes do a whole thing about how Linkedin was maybe a whole weird Networking Cult of mutants failing upwards and glad handing each other??? Or was it 60 Minutes Australia, I forget. Maybe it was just a dream, of a world that was a little more anti-social media, who knows. Either way, we'll be getting some more info on things in the coming week. 

[Spamme54321]

BJ is confusing LinkedIn with the cult of mutant pumpers on this board LOL. And 'glad handing each other' is what the pumpers here do best!