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Bullboard - Stock Discussion Forum Spectral Medical Inc T.EDT

Alternate Symbol(s):  EDTXF

Spectral Medical Inc. is a Canada-based late-stage theragnostic company advancing therapeutic options for sepsis and septic shock. The Company develops and commercializes a treatment for septic shock utilizing its Endotoxin Activity Assay (EAA) diagnostic and the Toraymyxin therapeutic (PMX). PMX is a therapeutic hemoperfusion device that removes endotoxin, which can cause sepsis, from the... see more

TSX:EDT - Post Discussion

Spectral Medical Inc > Spectral on Linkedin Today
View:
Post by TechOne on Dec 12, 2024 12:57pm

Spectral on Linkedin Today

Research indicates that elevated hashtagendotoxin levels correlate with disease severity and patient outcomes, making EAA a valuable tool in clinical settings.

The endotoxin activity assay (EAA) has confirmed the link between systemic LPS presence and Gram-negative infections in hospitalized patients.

In the MEDIC trial, the EAA demonstrated a sensitivity of 85.3% for detecting Gram-negative infections and a negative predictive value of 98.6% for ruling them out.

Endotoxemia was also found in patients with Gram-positive infections and those without culture-positive organisms, suggesting LPS may translocate from the gut.

High levels of endotoxin (EA ≥0.6) were associated with an increased risk of severe hashtagsepsis and ICU mortality.

The EAA can help identify patients who may benefit from anti-endotoxin therapies, as seen in preliminary studies combining EAA with hemoperfusion devices.

The assay is useful in ruling out Gram-negative infections in ICU patients presenting with systemic inflammatory responses without clear infection sources.

The combination of diagnostic assays with specific therapeutic agents may enhance treatment efficacy and patient selection

https://buff.ly/3Bfc38v
Comment by hmmmmmmmm on Dec 12, 2024 1:39pm
Correct me if I'm wrong, but it does seem all their posts/ claims on LinkedIn are re:  EAA
Comment by PezDalatoYou on Dec 12, 2024 2:31pm
They have lots of LinkedIn posts on PMX/polymyxin/Tigris trial/etc.
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