TSX:MSCL - Post Discussion
Post by
db2067 on Nov 25, 2021 10:04pm
Satellos / U of T connection
Some of the work happening here at U of T is for Satellos - testing on human muscle tissue - sort of a big deal - "... to enable human testing of candidate drugs in a ‘personalized’ culture assay, we will incorporate induced pluripotent stem cells, derived from DMD patients, to create DMD MEndR, and then use this assay to evaluate Satellos’ lead therapeutic compounds." UNIVERSITY OF TORONTO ENGINEERING NEWS U of T researchers’ lab-grown muscles used to study Duchenne muscular dystrophy, develop treatments https://news.engineering.utoronto.ca/u-of-t-researchers-lab-grown-muscles-used-to-study-duchenne-muscular-dystrophy-develop-treatments/
Inside a Petri dish in a lab at the University of Toronto is a muscle — made from scratch using human stem cells — that has Duchenne muscular dystrophy (DMD). ... “The DMD pre-clinical assays being developed by Gilbert and Stewart are a critical facet of the translational pipeline, making it possible to test current and future therapeutics in the context of human cells,” says Dr. Rudnicki [Satellos], senior scientist and director of the regenerative medicine program and Sprott Centre for Stem Cell Research at the Ottawa Hospital Research Institute.
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