TSX:MSCL - Post Discussion
Post by
db2067 on Jul 04, 2022 10:02am
Defeat Duchenne Canada
https://musculardystrophynews.com/2022/06/16/defeat-duchenne-canada-grants-1m-dmd-treatment-research/ Defeat Duchenne Canada grant recipients for this year include Michael Rudnicki, PhD, director of the Regenerative Medicine Program at the Ottawa Hospital Research Institute, Ottawa, Ontario. He’s discovered a protein called Wnt7a that could become a DMD treatment candidate due to its ability to repair muscle damage. Rudnicki will work to deliver the protein via circulation to all bodily muscles. In particular, his team is investigating exosomes, small vesicles found naturally in human bodies and which carry information between cells. Through the project, titled “Systemic Delivery of Wnt7a for Treating Duchenne Muscular Dystrophy,” Rudnicki and his lab will engineer new versions of exosomes carrying Wnt7a for delivery to muscle cells. The hope is that the prospective therapy will stimulate the muscles’ own capacity for regeneration and growth, independent of the underlying mutation.
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