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Bullboard - Stock Discussion Forum Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and... see more

TSX:ONC - Post Discussion

Oncolytics Biotech Inc > Today's Clinical Results Seem Promising
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Post by markymark11 on May 20, 2021 4:56pm

Today's Clinical Results Seem Promising

Today's clinical update seems promising compared to other trials done in advanced pancreatic cancer.
 
In a study using acalabrutinib alone or with pembrolizumab, the overall response rate and disease control rate were 0% and 14.3% with monotherapy and 7.9% and 21.1% with combination therapy, respectively. [1]

Another study, using Durvalumab with or without Tremelimumab, reported an overall response rate of 3.1% for patients treated with combination therapy and 0% for patients treated with monotherapy. The disease control rate at 3 months was 9.4% for patients treated with combination therapy and 6.1% for patients treated with monotherapy. [2]
 
Oncolytics reports that their study achieved a disease control rate of 42%. I look forward to reading the full poster presentation when it's released in June.


[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057435 - Randomized phase II study of the Bruton tyrosine kinase inhibitor acalabrutinib, alone or with pembrolizumab in patients with advanced pancreatic cancer

[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647002 - Durvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Comment by askretka on May 21, 2021 10:22am
Yep! Big Pharma has the eggs. Oncolytics Biotech has the BACON, and big pharma wants BACON to go with their eggs! Can't make it any simpler than that for anyone who want to invest. Cheers!
Comment by fox7mf on May 21, 2021 10:36am
Agreed 100%, which is why I'm inclined to believe buyout talks with Big Pharma are in motion and a deal could come anytime within the next few months. The science saves lives...the price will reflect that. IMO.
Comment by Capitalista on May 22, 2021 11:23am
Mmmmmmmm.  Bacon!
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