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Bullboard - Stock Discussion Forum Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and... see more

TSX:ONC - Post Discussion

Oncolytics Biotech Inc > Curious about Monday at ASH, nothing noted about this
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Post by canadafan on Dec 11, 2021 10:38pm

Curious about Monday at ASH, nothing noted about this

https://ash.confex.com/ash/2021/webprogram/Paper151575.html

This is the first glance of ONC/Pela/ Reolysen getting into Luekemia, study
Alongside BMS of all companies.
Curious why zero press on this one. Perhaps Tuesday as the presention is MOnday eve.
Comment by Noteable on Dec 12, 2021 3:05pm
Just for clarification - 'Reolysin' was the trade name given to ONCY's TD3 strain of reovirus for human adiministration, when Thompson was CEO, and is still used by many researchers to describe pelareorep. However, the generic name of the TD3 strain is 'pelareorep' and this generic name was granted by the FDA after this regulatory agency stated that the name 'Reolysin' ...more  
Comment by lonc17 on Dec 12, 2021 6:37pm
Reolysin was the trade name in use for about fifiteen years.  The reason given by ONC for the change to Pelareorep has always stuck me as being completely fabricated and pure bogus nonsense.  I believe the name was changed from Reolysin to Pelareorep for strategic purposes... to help bury fifteen years worth of failed clinical trials and "re-brand" the virus as they move ever ...more  
Comment by inthno on Dec 12, 2021 6:44pm
Hey note, thanks for your thoughts on the name change to pela from Reolysin but that has always confused me as there are a multitude of drugs out there with the same similar name and none of them have had to change from what I know, I believe that said that it sounded too similar to bromycin, don't really think you could mix that one up and I believe that the trademark name in Europe was ...more  
Comment by Noteable on Dec 12, 2021 9:07pm
ONCY has better things to do other than chasing around to produce evidence of the FDA's request to refer to ONCY'S TD3v reovirus under the generic name 'pelareorep' which is the nomenclature that the FDA provided. It was an easy decision for ONCY to make. If anyone wants evidence they can do the work themselves by searcing the FDA site. Have fun.
Comment by Noteable on Dec 12, 2021 9:24pm
Every listed drug requires a generic name. For instance the generic name for the drug with the trade name Asprin is acetaminophen. When ONCY developed the variant of the TD3 reovirus which is known as TD3v reovirus and ONCY obtained a composition of matter patent for this variant which expires in 2028 and extendable to 2033, the variant did not have a generic name even though it now had ...more  
Comment by Noteable on Dec 12, 2021 9:29pm
Correction: Asprin is acetylsalicylic acid and Tylenol is acetaminophen.
Comment by Conquistador1 on Dec 16, 2021 4:20pm
THe generic name for aspirin is acetylsalicylic acid. I haven't owned ONC for a few years. I sold it some time after they dropped the Reolysin trade mark. I agree that the trade mark carried either negative value, or they forgot to renew the trade mark which lapsed on May 31, 2018.  I doubt the FDA asked them to change it. I don't have a dog in this race but the best thing that ...more  
Comment by canadafan on Dec 17, 2021 9:27am
Interesting you note you have no dog in this race, yet recommended selling @ $3ps. one needs to note  there are a handful of analysts with 12 month targets of between $6ps & $15Ps. you are 100% correct, a $3ps would not be recommended or accepted. Nor would it be offered. $10ps maybe. recall, ONC has an active partnership with China partner A.N.  That alone is worth much more ...more  
Comment by unNoteable on Dec 17, 2021 9:56am
Canadafan - ONCY is worth whatever the market prices it as... After 20+ years they still do not have in vivo data credible enough to entice big pharma to invest in a Phase III. When this was $3, you were saying how this company was going to the moon, and how much it was undervalued. If anyone had taken your advice and bought in for fear of missing out, they would be on more than a 50% loss... I ...more  
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