Post by
askretka on Feb 14, 2022 11:39pm
For Notable. From "Science" 9Dec 21
https://www.science.org/doi/10.1126/science.abk3436 Its the abstract only from well known Oncology virus researcher Alan Melcher. It's the Abstract only but I found this part very interesting. ------------------------------------------ (1). This view has now been largely replaced by a model in which infection of the tumor by the virus makes it more visible to the immune system for recognition and attack. Tumor cell killing by the virus and/or immune effector cells EFFECTIVELY GENERATE AN IN SITU VACCINE, with tumor antigens released into a microenvironment modified by viral infection to reverse tumor-induced immune suppression. -------------------------------------------------------- Cheers!!!
Comment by
askretka on Feb 16, 2022 12:29pm
Thanks Notable. Things seem a bit too for me on the CAR-T front, but after the recent news on CAR-T 10 year survival rate and Novartis possibly with an in Vivo CAR-T in the works, timing for a CAR-T/Pela deal couldn't be better in my opinion. Cheers!!!!