Oncolytics Biotech Inc T.ONC

Monday

[lonc17]

Things to think about before Monday morning. 

A look on clincialtrials shows 245 cancer studies presently recruiting or active:
https://clinicaltrials.gov/ct2/results?cond=Cancer&term=&type=&rslt=&recrs=a&age_v=&gndr=&intr=&titles=&outc=&spons=&lead=&id=&cntry=DE&state=&city=hamburg&dist=&locn=&rsub=&strd_s=&strd_e=&prcd_s=&prcd_e=&sfpd_s=&sfpd_e=&rfpd_s=&rfpd_e=&lupd_s=&lupd_e=&sort=

A look at Dirk Arnolds linkedin shows hiim describing Goblet as one of AIO's "major trials"
https://it.linkedin.com/posts/dirk-arnold-7482a178_goblet-a-phase-iii-study-of-pelareorep-activity-6956625803358916608-v5VF?trk=public_profile_like_view

And it is interesting to see former Medical Officer Rita Laeufle reminding everyone that she designed the Goblet trial:
https://it.linkedin.com/posts/dirk-arnold-7482a178_oncolytics-activity-6990895915318321152-dxlj

[lonc17]

Things to think about before Monday morning.  A look on clincialtrials shows 245 cancer studies presently recruiting or active: edit.. (in Hambburg...location of Goblet) https://clinicaltrials.gov/ct2/results?cond=Cancer&term=&type=&rslt=&recrs=a&age_v=&gndr=&intr=&titles=&outc=&spons=&lead=&id=&cntry=DE&state=&city=hamburg&

[westcoast1000]

Thanks for these interesting links, Ionc17.

[westcoast1000]

Here is some useful , plain language information  about Goblet drawn from Ionc's links below: Abstract Most gastrointestinal (GI) cancers have microsatellite-stable (MSS) tumors, which have an immunologically ‘cold’ phenotype with fewer genetic mutations, reduced immune cell infiltration and downregulated immune checkpoint proteins. These attributes make MSS tumors

[Noteable]

Link to the Dirk paper .. https://www.futuremedicine.com/doi/10.2217/fon-2022-0453#.YtwNt7Ntolw.linkedin GOBLET: a phase I/II study of pelareorep and atezolizumab +/- chemo in advanced or metastatic gastrointestinal cancers Maike Collienne  ,  Houra Loghmani ,  Thomas Charles Heineman  &  Dirk Arnold

[Noteable]

Should read Dirk Arnold paper ...