Post by
canadafan on Dec 29, 2022 3:55pm
Just the facts …need to be understood
So this is a chat room.
Some look here for information, some provide information & some instead of any semblance of logic, attack those providing the information.
The only thing personal attacks & Ad Hominem accomplish is to degrade the quality of the forum.
Again;
A challenge.
I will post 5-6 recent news/ data & accomplishments from ONC.
please I welcome solid discussion to refute any of these points, preferably by number.
1. Onc just received fast track designation for a Pelareorep & tecentriq ( Roche), co- therapy trial.
2.:It was announced November 10th, that the Goblet trial had a 69% response rate. Triple the industry standard of care. Including one full response. Meaning that patient ( so far) , was cured..unheard of for panc cancer. One of the deadliest..hence the fast track approval.
3. on December 8th , ONC's partner Adlai Nortye announced clinical data, demonstrating Anti- cancer Activity. With palareorep & Paclitaxel ( Pfizer )..leading to next step of phase 3 registration.
4. Aware-1 results published at breast cancer symposium, showing positive results ( Onc & Pfizer).
5. Onc & Pfizer have a 90 day mutual exclusive " data blackout" , giving Pfizer first right of refusal to offer a licensing deal with Onc. ...MBc phase 3 trial registration.
6. Onc is now in position & has stated so, to partner with a company to license both panc cancer & Mbc...They have all said those discussions are " on- going, with multiple large pharma"
7. There are 3 separate smaller items; The on going co therapy with Incyte. The on- going CAR-t, trials & pharma discussions. About 2-3 other new trials. Neither oF which has shown any bad results.
So, there you go: Not pumping, just stating facts.
please I encourage legitimate discussions on any of these.
enjoy
Comment by
Azzak34 on Dec 29, 2022 4:38pm
This post has been removed in accordance with Community Policy
Comment by
westcoast1000 on Dec 29, 2022 5:13pm
Thanks CF for this timely summary, as the year ends and we look to partnerships next year.
Comment by
inthno on Dec 29, 2022 6:43pm
Canadafan Agree on all points that you have stated. Big question will it be partnership or buyout, Will it come down to what Coffey wants or what BP desires the most. What it will come down to is cooperation and give and take on both sides of the table so lets hope that all are reasonable. As to what is reasonable, well that is the question.
Comment by
Buckhenry on Dec 29, 2022 7:49pm
when is the phase 3 for pancreatic and breast cancer going to begin? who is funding that?
Comment by
Buckhenry on Dec 30, 2022 12:36pm
we could have read this same post each year for the last 3 years. SOS different year. and no im not selling and moving on...here till the fat lady pays off or goes bankruptcy
Comment by
jimsenior on Dec 30, 2022 6:24pm
I was reading today about ADCs on Fierce Biotech. I know nothing about ADCs. I do think that an ADC was used in Cohorts 4, 5 and 6 of Aware-1. Can anyone elaborate on the relationship of ADCs and pelareorep. TIA
Comment by
Buckhenry on Dec 30, 2022 6:46pm
I think you meant to say..... steady array of realists trying to keep you forever pumping dreamers in check and bring you back to reality. we realists tell it like it is.... you folks bash us for that beacuase it pokes holes in your dreams. dreaming is fine as long as its tempered with the reality.
Comment by
Buckhenry on Dec 29, 2022 7:46pm
I like ur idea but its only ur idea. no fact unless ur sitting on the board. analysts dont count for sh!t in my book.
Comment by
Buckhenry on Dec 29, 2022 9:08pm
This post has been removed in accordance with Community Policy
Comment by
Buckhenry on Dec 29, 2022 9:15pm
you wrote a whole dissertation and did not answer my question. go hack and re read... the stuff you keep posting is old news.