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Bullboard - Stock Discussion Forum Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and... see more

TSX:ONC - Post Discussion

Oncolytics Biotech Inc > Pfizer turns over Bravencio to Merck.
View:
Post by askretka on Mar 27, 2023 6:47pm

Pfizer turns over Bravencio to Merck.

https://endpts.com/merck-kgaa-takes-back-control-of-pd-l1-cancer-drug-as-pfizer-alliance-ends/
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Merck  vs Roche now?
Comment by Noteable on Mar 27, 2023 7:03pm
Along with Pfizer wanting to avoid potential antitrust issues on the acquisition of Seagen, by divesting in Bavencio (avelumab),  Pfizer is developing its own PD-1 immune checkpoint inhibitor - sasanlimab, which can be administered subqutaneously (subQ). Roche's (atezolizumab)Tecentriq  and Merck's (pembrolizumab) Keytruda have also developed their own subQ immune checkpoint ...more  
Comment by Noteable on Mar 27, 2023 7:50pm
GSK's PD-1 immune checkpoint inhibitor Jemperli could also become part of the group looking to combine with ONCY's pelareorep. https://www.fiercepharma.com/pharma/new-pd-1-showdown-gsks-jemperli-lost-chance-winning-streak-over-mercks-keytruda
Comment by Noteable on Mar 27, 2023 8:08pm
ONCY's Phase 2 GOBLET clinical study includes a cohort involving pelareorep in combination with atezolizumab in 1st line MSI (microsatellite instability)-high metastatic colorectal cancer patients in which GSK's PD-1 checkpoint inhibitor Jemperli and Merck's Keytruda are currently competing to gain prominence, as described in the previous post's attached link. https://www ...more  
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