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Bullboard - Stock Discussion Forum Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and... see more

TSX:ONC - Post Discussion

Oncolytics Biotech Inc > Pelareorep synergizes with azacitidine
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Post by askretka on Jul 24, 2023 10:59pm

Pelareorep synergizes with azacitidine

The trial being stopped, ENHANCE, was studying the use ofs magrolimab plus a type of chemotherapy called azacitidine (Vidaza) in patients with higher-risk myelodysplastic syndromes, or MDS.

I always found it interesting that when magrolimab study was stopped by FDA temporary the first time 

We had a press release around the same time that said Pelareorep was synergistic in leukemia with azacitidine but we didn't get noticed really. 



https://www.newswire.ca/news-releases/oncolytics-biotech-r-announces-the-presentation-of-preclinical-data-demonstrating-the-synergistic-anti-leukemic-effects-of-pelareorep-combined-with-azacitidine-at-the-2021-american-society-of-hematology-annual-meeting-889202448.html
Comment by jimsenior on Jul 25, 2023 10:15am
I noticed Immugene was mentioned on another site. Perhaps it is of interest to note that Dr. Laeufle who was closely involved with the GOBLET design, left ONC/Y to work for a time at Immugene. It is not too much of a stretch to imagine that she was aiding and advising pharma on oncolytic viruses. That is just idle speculation on my part. The excellent design of GOBLET is not. We shall patiently ...more  
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