Oncolytics Biotech Inc T.ONC

History Repeats

[Quentin30]

For those who like charts, there are certain months when ONCY pps rises significantly, usually in expectation of great data/announcements around the time of a particular conference.

Why do I expect the price to stagenate or fall back to $1.10-$1.25 lows again by early next year..? Well why did ONCY do a financing so cheaply compared to the highs of 2023... probably because management was well aware there would be no other real inflection points to keep the price rising. They have sold stock into highs for as long as I've been invested. If Matt thought there was truly earth shattering news to announce, he would have held off on the financing... so I conclude that for the next 3-5 months, this is dead in the water... 

I would also expect (hope) another decent run in late April/May, before the announcement of start of Phase III. Wouldn't it be nice for the pps to get above $3 and keep going for once.

Although why ONCY cannot start the Phase III with the combo they told us about in June already is beyond me. They shuld have amended the study protocol by now, and had that agreed by FDA/ ethics committees.

Also, IND213 confirmed statistically, that the Pela Triplet is better than Pax alone. So they won't be running a phase III with a CPI anymore for that indication... I do not believe they are waiting for Bracelet-1 to mature (that was the argument for the failed Phase III head and neck trial, and look where that ended up ). Pure speculation on my part, but I think ONCY will pull a fast one, and trash the mBC Phase III trial, and focus on two shots at goal with different combos for Panc.

Whilst these clowns have been stating they are advancing towards a registrational study for 6 years straight (overtaken by the occasional snail), I think the panc trial probabcly could be ONCY's saviour. By mid 2025, it will finally be clear if this works or not... Whatever the pumpers claim, this is STILL a risky investment.

any thoughts ?

[venture009]

It's hard to argue your points. They all seem logical. The financing really did raise some red flags and the fact they spent 5 years trying to prove their own trial is disgusting.  About the only thing that my prove to be opposite would be if FDA grants an AA. Big if I know.

[CaseyL]

Last conference call sucked. They never had trouble talking about timelines, nevertheless not achieving them. But to not reflect on the obvious has me infuriated. 

[Quentin30]

Venture009 - Neither Matt nor Heineken ever speak about Accelerated Approval. They need a confirmed biomarker, but they always fall short in calls of stating defintively that they have one. Perhaps this is why they want to wait for the mBC Bracelet OS data - to find a closer correlation. But then again, we already know that patient numbers were too thin on the ground for any meaningful statistical

[Azzak34]

Should we all sell Quentin? Is it all over for us? 

[Quentin30]

no insult today Azzak34..?? LOL Well I you are in, and underwater, then it's probably not worth selling. ONCY oculd make a partnership announcement anytime... nobody knows this. Assuming the Panc data is for real, then it's probably worth waiting for further drops. If history repeats, then I see this falling back to $1.10-1.25 area, before it climbs. As I've said before, I have a

[Azzak34]

No need to insult you on a daily basis, why don't we just have a standing order on "you're a deceitful, weasel, idiot"?  I'm still up but if this goes to $0.05 I'll be holding. We call that conviction of one's beliefs Quento.  You aren't underwater, you have no shares here.  If you're right then any price is risky, please tell me you

[Quentin30]

and there was me thinking you'd changed...  a bit o=like the pumpers saying oh it's different this time..!! And you have no idea if I own shares or not. Azzak. All you can do is speculate.. and that's why you'll still be holding this at $0.05 and singing Matt's praises when he says ONCY are abandoning Panc and mBC because they now see a signal for muscle invasive bladder

[Azzak34]

My absolute favorite is when you dopes accuse people of speculation then, in the same paragraph, of sorts, wildly speculate. Do you not realize that when you're typing, albeit shoddily?  Yeah... I said I was holding. There's no need to tell me to keep holding, I've said it repeatedly, I will be holding until that glorious day. We have as many days together as it takes, exciting.&

[Quentin30]

I would gladly see ONCY go bust and know that you were holding on like a lemon all the way down Azzak. In fact that makes me all giddy. I didn't epect a keyboard warrior like you to accept my challenge... ONCY or CRPR - buy today to see who makes the most by 31-Dec... Now get off the sole of my boot would ya.

[Azzak34]

Haha but you'd lose out too, you're a major shareholder!!  I'd be delighted to take you up on that challenge. Bahahaha let's do a zoom call and I'll record it so all the folks on here can laugh at you shrivel up like the little worm you are. 

[Quentin30]

Why are you so vile ? there must be a reason. I don't see you post anything of substance, either with any original thought, any solid reasons for why you're a pumper... nothing... but bile... yeah... let's do a zoom call, what fun that would be for me... dya think..? so... we can do the challenge anyway. .. assuming a virtual investment of 10k today... closing price of CRPR today is

[Azzak34]

Haha don't get upset sweetie it's all just online chat, no need to get emotional.  I think you'd back up off your tough guy talk and maybe be a little more pleasant.  Should we get t-shirts and see if we can maybe televise it for Wallstreet bets too? Just on the % change from today idiot, doesn't have to be complicated. 

[Quentin30]

LOL... not upset 'sweetie'... I see ONCY has zero Phase III's in scope now... what's the positive spin on this... Everyone who digs into ONCY's data seems to back off... now let's see how Crispr does today shall we...?

[Azzak34]

Aww you were all upset last night babe? How'd you sleep? Teary eyed...  You guys were only down 7% yesterday so hopefully turn around for you today? 

[13X2413]

You might want to take this back. 

[Azzak34]

Nope, watch the comeback this afternoon. We can revisit this. 

[13X2413]

Azzack/Noteable-I hope you're right. I know you'll probably toss some type of insult at me, but what is positive about anything that came out today?

[fasttrack5]

https://stockhouse.com/news/press-releases/2023/11/09/oncolytics-announces-the-anal-cancer-cohort-of-the-goblet-phase-1-2-study-of

[Azzak34]

We cured a person with Anal cancer and tripled the OR rate from the SOC in the indication. More proof Pela is going to be the SOC in multiple indications. That's pretty good. 

[venture009]

Azzak, what type of announcement are you expecting? We are now trending toward the NASDQ $1 requirement and we all need to be concerned. There seems to be no support for the price. As pointed out here, there have been so many screw ups by this management that there is very little chance that investors want to take a risk with these guys anymore. 

[Azzak34]

Then sell up and move on. No vitriol from me, just take your loss and put it down to experience. You have to do what you think is right for you.  Read the press release of the Goblet results, then look at all the other recent results and tell me this company doesn't have the goods with Pela. 

[Quentin30]

well, one complete response can be a fluke, two... and well, now things start to get interesting. From the latest data. Furthermore, we've seen another complete response in an indication where checkpoint inhibitor therapy alone has had limited success historically, which bodes well for the potential of pelareorep to work synergistically with multiple immunotherapies in multiple tumor types

[13X2413]

Like I mentioned earlier, there's nothing positive in this latest blurb by the company. One only has to look at the market reaction today.  Just another effort by management to stretch timelines in an effort to prop this company up. 

[Azzak34]

Then you're a liar or an idiot. Did you not see the Goblet results? Even that clown Quentin is starting realize what's coming. 

[jh1970]

Looks like a company has a goods, BUT market doesn't belive in chance that this managment is able to cross finish line. Enough is enough. 

[venture009]

The patient trial size has always been a concern of mine. Not sure what the thinking was having a statistically insignificant number.  Why not insist that the trial no. be at least 50.

[13X2413]

Because it would be a better indication of the effectiveness of the treatment and they are worried about that.  They can dance around smaller numbers.  Their dance moves are getting tiresome, hence, the never ending drop in share price. 

[ONCInvestor]

Another good post from Quentin.  I too am unhappy with Bracelet. They either chose the wrong CPI or the wrong trial design to show efficacy with Avelumab. And we're out of time now to backtrack. My own opinion is that ONC will never run a Phase III with mbc. It's pancreatic or bust for ONC now. And that's why I'm quite disturbed that we have not executed any definitive

[Quentin30]

ONCInvestor - The first three patients on Bracelet-1 would have been those taking the triplet therapy - run-in trial done for safety reasons... The first OS data they had should have been from these three patients and ONCY would have known damn well how this compared with Pela+Pax alone. They kept telling investors that this trial was done to derisk the prospective Phase III, and to ensure a

[Journeytc]

Quentin history does repeat itself!!!  Let's talk phase 3 experience.  It begins with ONC's head and neck failure. ONC failed the Head and Neck Trial on two counts.   First a large group of patients dropped out with flu like symptoms.   You know the best responders.  Sound familiar.   The second reason is in the last 6 months of a 6 year

[13X2413]

Damn! I hate it when you post because it explains so much and makes so much sense as to why this has been going straight into the dumper.  Thanks, I think. :)

[Journeytc]

There's an important detail regarding.. going to the dumpster.   Matt did a huge promote after they hired the chief med officer to put together the phase 3 breast cancer trial.   A on partnership and phase 3 initiation.  Matt carried this illusion for 8 months after resignation of the chief med officer.  He squeezed the hell out of the ATMs knowing coarse had

[JohnnyYeg]

So JTC - what exactly ARE your credentials to be calling out the scientists involved in a biotech development company??

[Journeytc]

Credentials.. scientist? No.  Work in biotech? No.  In business generally.. a little bit. Johnny.   I take Matt at his word when he says the Head and Neck phase 3 failed because...   I am on stockhouse record just before the key opinion leader conference call stating my concern about whether or not ONC wrote treatment protocols for flu like symptoms into the Breast