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Bullboard - Stock Discussion Forum Oncolytics Biotech Inc T.ONC

Alternate Symbol(s):  ONCY

Oncolytics Biotech Inc. is a clinical-stage biotechnology company. The Company is focused on developing pelareorep, an intravenously delivered immunotherapeutic agent that activates the innate and adaptive immune systems and weakens tumor defense mechanisms. This compound induces anti-cancer immune responses and promotes an inflamed tumor phenotype turning cold tumors hot through innate and... see more

TSX:ONC - Post Discussion

Oncolytics Biotech Inc > Todays Announcement Goblet Expansion
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Post by Journeytc on May 09, 2024 10:57am

Todays Announcement Goblet Expansion

Pure specilation on my part.  GOBLET achieved magnificent result in the GOBLET pancreatic trial with the pela ICI combo.    So why fuss with success and expand Goblet to include Folfirinix +- ICI?    High cost might limit access to treatment, limit who can be saved and reduce treatment population size.   And treatment population size affects earnings.  Pancreatic cancer is a much smaller indication tham breast and if population is further reduced on cost thats a problem.  Im guessing treatment costs would be 300,000 us dollars per patient.   150,000 dollars for pela and 150,000 dollars for ICI. 
If ONC with biomarker, can identify a large sub group within the population responding to the combo treatment, thats a big deal for patients, for cost and safety.  And i think its portends whats to come for pela in the treatment of all sorts of different cancer indications. 
Todays announcement is great especially sonce effort is sponsored by someone else.
Comment by Noteable on May 09, 2024 11:07am
All the "fuss" is about gaining a larger/bigger market share of pancreatic cancer market by being able to initate treatment both in the early and advanced stages through the treatment of both older and younger patients.
Comment by Noteable on May 09, 2024 11:52am
Tell my why CADL is worth US$10 when they only have Phase 2 results in 13 patients using intratumorally injected herpes virus in patients with non-metastatic borderline resectable pancreatic cancer.
Comment by Peladawn on May 09, 2024 12:19pm
Note....whatever their sp is right now, the good news is that a month ago it was only $1.58....that's how quickly it can and does change.....
Comment by Noteable on May 09, 2024 12:34pm
A very weak answer to my question, since CADL is up to around US11 on very little comparable news to ONCY, I won't go into the other reasons why ... since my question was rhetorical in its very nature.
Comment by Noteable on May 09, 2024 12:50pm
CADL has set itself for a lawsuit based on the following April 04, 2024 press release statement by Paul Peter Tak, MD, PhD, FMedSci, President and Chief Executive Officer of Candel on the conversion of pancreatic cancer into a chronic  disease because of CAN-2409. ...  "CAN-2409 is able to change the balance between the tumor and the patient’s anti-tumor immune ...more  
Comment by Angler101 on May 09, 2024 1:07pm
Noteable.....Pela's answer to your question was nowhere even close to as weak as your response to my point that you falsely accuse someone of insurrection when he has never been convicted of such, or even for that matter even ever been charged......you recused to even reply, and THAT, my arrogant friend, is the very definition of weak!....especially considering the fact that you are guilty of ...more  
Comment by Noteable on May 09, 2024 1:11pm
Go try your bait somewhere else.
Comment by Angler101 on May 09, 2024 1:16pm
bait, what bait?....I simply would like you to cut and paste proof that Trump is guilty of insurrection, considering you seemingly have no problem accusing him of it...otherwise, that alone sets you up for a defammation lawsuit...
Comment by Noteable on May 09, 2024 1:21pm
Angler101 - do you have a good lawyer, you will need one.
Comment by Peladawn on May 09, 2024 1:25pm
Why would I need a lawyer?......tell me exactly what I have done to you, that you haven't done to Donald Trump!
Comment by Peladawn on May 09, 2024 1:28pm
All you have to do is cut and paste proof that Trump is guilty of insurrection, and I will apologize for making a point and we can call it a day!
Comment by Noteable on May 09, 2024 1:29pm
Well isn't that interesting  ...now we see that Angler101 is also Peladawn. 
Comment by Peladawn on May 09, 2024 1:33pm
This post has been removed in accordance with Community Policy
Comment by 13X2413 on May 09, 2024 1:57pm
OMG. Move on. Focus! ONC showing some life.  Stop fighting kids or you'll have to go sit in a corner. 
Comment by Buckhenry on May 09, 2024 2:16pm
The pumpers trying to move focus elsewhere and talk about things they know even less about cause nothing is going on with this dud. 
Comment by Azzak34 on May 09, 2024 2:17pm
Shut up Buck, let them scrap it out. Don't be a lil beeatch on the sidelines. 
Comment by Buckhenry on May 09, 2024 2:25pm
Wonder who MC is in collusion with???
Comment by Azzak34 on May 09, 2024 2:33pm
Your mum. Colludes every Friday at the Motel 6 down the road from you. 
Comment by Buckhenry on May 09, 2024 3:12pm
What about unnoteables cult following.... cults  don't generally end well. 
Comment by Peladawn on May 09, 2024 2:01pm
Gee, what a surprise!...still no proof of insurrection.....or Russian collusion....always ready to repeat the false accusations, but never the slightest hint of proof....
Comment by Noteable on May 09, 2024 2:03pm
Trump's violation of the US Insurrection Act .. see 2022 link. Trump’s legal duty closely resembled a police officer’s. His duty, however, was imposed by Article II, Section 3 of the Constitution, which provides: “[The president] shall take Care that the Laws be faithfully executed.”  He violated his duty under the Constitution and in so doing, under the Insurrection Act. https://www ...more  
Comment by Noteable on May 09, 2024 2:08pm
 As concluded in the cited legal opinion of Trump's Insurrection  "Attorney General Garland has said and reiterated: “The Justice Department remains committed to holding all January 6th perpetrators, at any level, accountable under law. … We will follow the facts wherever they lead.” Neither the Department’s investigation nor the Select Committee’s is nearing the ...more  
Comment by Peladawn on May 09, 2024 2:20pm
Yeah....just like all the "dazzling" proof that pencil neck Adam Schiff lied to the Senate and the American people about for four years about how Trump "colluded" with Russia to overthrow the election, and still to this day he hasn't managed to come up with a shred of proof.
Comment by Peladawn on May 09, 2024 2:14pm
LOL.....that's from the "House Select Comittee"....very aptly named because they "selected" all Trump hating Democrats, and two Trump hating republicans, and disallowed anyone else.....and even after months of that orchestrated kangaroo court sham, and a waste of millions of taxpayer dollars, they still couldn't come up with enough to officially charge Trump with ...more  
Comment by Noteable on May 09, 2024 3:07pm
My goodness Trump's Cult is dangerous in their loyalty to him as a person. Very much like other cult members in autocratic dictatorships like Russia, China, and N. Korea - which Trump especially likes.- Poland, Turkey, India, Brazil, Chile, Argentina, etc.
Comment by Noteable on May 09, 2024 3:18pm
I'm sorry but Peladawn, but that how democracy works. Those like Marjorie Taylor Green could have become part of the Bipartisan Select Committee but she and other Trump Cult members refused. Now most others of the Republic Party are having different thoughts about their boycott, including Mitch McConnell and former Republic Speakers of the House..
Comment by Noteable on May 09, 2024 3:22pm
It took courage for many Republicans to oppose Trump's Cult. Unfortunately not many Republicans have that sort of fortitude and instead just " fall into line" with their power hungry loyalty. 
Comment by CMHarring218431 on May 09, 2024 3:47pm
Noteable....The real truth is that Trump will win the election, in spite of the hate democrats have for him, because of how absolutely horrible Biden has done. People are sick of his policies and loyalty to far left. From inflation to the border to his international failures to his attempts to win elections by giving handouts in the billions of dollars I.e., student loan bailout etc. What really ...more  
Comment by Peladawn on May 09, 2024 4:16pm
Bang on CMH!.....I agree 100% with everything you said.....don't even try to convince Notable....easy to see he's way too far gone....sometimes Trump Derangement Syndrome can progress to a permanent condition...... hey, let's get together later for some Yoga and meditation,.....lol!
Comment by Noteable on May 09, 2024 4:23pm
If you Peladawn aka Angler don't like to read what I say then that just further proves your closed minded Cult membership. 
Comment by Peladawn on May 09, 2024 4:27pm
See what I mean, CMH?.....WAY too far gone!
Comment by Buckhenry on May 09, 2024 4:27pm
Finally..  Unnoteable talking about something he knows a little about.... very little. 
Comment by Buckhenry on May 09, 2024 5:28pm
These pumpers sure don't like anyone pouring water on their woke narrative fire here. We should all love and accept each other's views... you know that's what DEI is all about... pukes here...
Comment by Azzak34 on May 09, 2024 5:35pm
Bahahaha Bucky gettin in on the policital action!!! Give us more Dumper, what's your take on the geopolitical outlook for us all?  Everyone sit back and relax, Bucktard is gonna fix it all...... go Buck. 
Comment by Peladawn on May 09, 2024 5:48pm
Yehaaaaa!......go Buckster!....
Comment by Buckhenry on May 09, 2024 5:51pm
The pumpers definition of DEI  is Division Exclusion..and Intrusion...
Comment by Azzak34 on May 09, 2024 5:54pm
Thats some powerful stuff there Buckster. Kay, now do BDS. What's the pumpers definition of that? 
Comment by Peladawn on May 09, 2024 5:55pm
Well, Bucky, you should know all about intrusion.
Comment by ENEMENEMYNEMO on May 09, 2024 6:41pm
Wow.  Blown away by the news!  Three "potential " phase 3 studies but no cash to pay for it and no partners. Lookin pretty rosie guys!
Comment by Peladawn on May 09, 2024 7:22pm
Yeah, that's exactly right, EMEMEmo buana bimo.......we've had nothing but positive trial news....so it only stands to reason how no big pharma could ever possibly be interested in joining Up somehow!
Comment by Noteable on May 09, 2024 4:20pm
Those are all far right wing talking points that many have heard far too often ... particularly those referencing the "common man', yet it remains that the billionaires who are funding their far right wing opinions and talking points .. like inflation and the border - when geopolitics and Chinese/Mexican gangs are primarily responsible for the very lucrative practice of 'human ...more  
Comment by Noteable on May 09, 2024 4:40pm
Should read .. " .. yet it remains that the billionaires who are funding those far right wing opinions and talking points of inflation and the Mexican border" ...  when in fact it is those same billionaires who are profiting from Trump's Cult ... and the "human and gun smuggling" along with the drug trafficking that happens through the US/Mexican border .. What ...more  
Comment by CMHarring218431 on May 09, 2024 5:07pm
Noteable, I am going to refrain from replying and turning this into a political forum which I'm sure most members would rather not see. I'm right ....you're wrong. LOL If I was to joust with you back and forth, it would go nowhere. As my brother repeatedly says in his arguments....When he thinks he's right....You just don't listen. The obsession the left has with Trump is ...more  
Comment by Peladawn on May 09, 2024 4:47pm
BTW, Notable.....I have nothing personal against you, except when you're rude to my gal, but unfortunately, you lefties ALWAYS make it personal, and that is why the country is so divided....I am one of those "common man" lowly scum you speak of, and I, and millions of others like me, are tired of the blatant lies that you lefties might believe, each and every time,, but frankly, we ...more  
Comment by Noteable on May 09, 2024 1:13pm
Angler101 - Are you trying to falsely accuse me of feloney tax evasion. If so, you better get a good lawyer!!
Comment by Angler101 on May 09, 2024 1:20pm
What's the matter, Note, ol' boy?....you have a problem with being falsely accused?....well, then, maybe you should reconsider the next time you think about doing the same thing to others!
Comment by Noteable on May 09, 2024 1:26pm
Angler101 - your further self incrimination of falsely accusing me is proof enough of your guilt. You'll need a good lawyer.
Comment by Lesalpes29 on May 09, 2024 11:40am
5M is not that much if you consider the cost. The conditions are not met yet to have a big partner with big $ to step in it seems. GL
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