Theratechnologies Inc T.TH

Breast cancer

[scarlet1967]

Spartrap just posted this research study from university of Gothenburg in Sweden published recently.
Read page 40!
https://gupea.ub.gu.se/bitstream/2077/66821/2/gupea_2077_66821_2.pdf

[scarlet1967]

https://stocktwits.com/Spartrap/message/283183986  

[qwerty22]

It really doesn't take much to show if THTX's drug has an inhibitory effect of this progranulin/sortilin mechanism. Basically all you need to do is repeat the expt the Swede's did but replace the sortilin inhibitor with THTTX's drug and see if you get the same outcome, maybe throw in a few more controls as well like THTX's peptide-alone and docetaxel-alone but you get an answer

[scarlet1967]

“Progranulin and one of its signaling receptors sortilin have previously been shown to be involved in cancer stem cell propagation and in metastasis formation. Taken together, these results demonstrated that progranulin increased cell secretion of many proteins, several of them dependent on sortilin binding. It has previously been shown that progranulin increase metastasis formation via sortilin

[qwerty22]

It's proving the drug actually interferes with that process is what is required.

[scarlet1967]

Yes I sent it to Leah...