Theratechnologies Inc T.TH

Agencies should loosen up...

[scarlet1967]

With such a burden to cohorts and economies maybe it is about the time that agencies relax their expectations re the drug’s efficacy.

Results

“Acknowledgment and subsequent clinical action were more likely in patients whose examinations was ordered by primary care providers, whose examination results were not urgent, and who were in the ultrasound group. The overall diagnostic yield in patients who underwent clinical evaluation was nonalcoholic fatty liver disease in 70%, nonalcoholic steatohepatitis, in 6%, and alcoholic hepatitis in 17%. NAFLD is a significant public health issue, affecting a quarter of the US population, with direct costs estimated at $103 billion per year.”

https://www.jacr.org/article/S1546-1440(21)00379-3/fulltext

[Wino115]

Can't see that happening just yet.  In some ways, THTX may have been lucky in using the PLWH group for the previous two studies.  Diet and exercise would help a lot less.  It will be interesting to see in this Phase 3 the difference between the PLWH group and the general pop group. In a simple sense, one could ascribe any differences to the ARTs and other HIV issues.