Costs and Cost-effectiveness of ARV Regimens for Highly Treatment-Experienced People with Multidrug-Resistant HIV
For people with multidrug-resistant (MDR) HIV, an ARV regimen that includes intravenous IBA or oral fostemsavir can be effective in achieving viral suppression, but costly. Two cost-effectiveness analyses using independent simulation models have demonstrated that IBA-containing ARV regimens would substantially improve survival for people with MDR HIV but at a high cost per quality-adjusted life-year, given the high cost of IBA. However, the overall budget impact of such regimens would be relatively small, given the limited number of people for whom IBA would be necessary.32, 33