Theratechnologies Inc T.TH

Dr. Mace Rothenberg, MD

[jfm1330]

Oncology is going so bad that they just hired an expert advisor...



https://www.theratech.com/about/scientific-consultants-and-advisors

[PWIB123]

Isn't this standard practice?

[scarlet1967]

"Dr. Rothenberg recently retired from Pfizer where he served as Chief Medical Officer from 2019 to 2021.  During this time, the company initiated, completed, and obtained emergency use authorization for its COVID-19 vaccine.  Prior to that role, Mace led Clinical Development for Oncology at Pfizer from 2008 to 2018.  Over that 10 year period, his organization developed and

[Bucknelly21]

Is that sarcasm? quote=jfm1330]Oncology is going so bad that they just hired an expert advisor... https://www.theratech.com/about/scientific-consultants-and-advisors[/quote]  

[SPCEO1]

Glad to see you back!  I hope your health is not causing you any problems. I think the hiring of him at this time is likely the biggest hint we have yet that good thigs are happening on the TH-1902 front. THTX already knows enough from the phase 1a trial to not bring him on if it was going to be a dud. While we may still not see any signs of efficacy in phase 1a, THTX likely knows the

[palinc2000]

We have zero scientific data on Efficacy but we now have 4 fantastic hints  1- The smiling KOL s during the Kol Event 2- Some kind of a retainer paid to a retired doctor with a great track record 3- Chinese sniffing around 4/ Paul is extremely excited on Phase 1 Did I miss anything on Efficacy? I wish

[scarlet1967]

Also the fact that they are hiring scientists, preclinical and clinical project managers can be added to the hint list. I guess Jim if his statement was genuine is disappointed cause the speculations of reaching over 700mg/m2 by this and thar date turn out to be SPECULATIONS.

[Wino115]

i wouldn't say zero data on efficacy.  A lot of the pre clinical data is helpful, even if in non human hosts.  I am fully on board with the fact we have no human data at all around efficacy and the pre clinical needs to be validated.  So I don't disagree with you Palinc.  I've always been in the hard data in humans camp for our valuation step function jump. I

[palinc2000]

I thought it was clear that my comment on Efficacy was exclusively related to data on Efficacy during Phase 1 ,,,,I dont know of a single data ,Do you ? Of course there was efficacy during the pre clinical studies ,,,Otherwise they would not have initiated a Phase 1 

[SPCEO1]

And of course we all know there is no efficacy data yet released from the phase 1a trial. But if what TH does know that they have not yet shared is indicative of future success in cancer, might they be quite sensibly looking for experts like Dr. Rothenberg to add to their team? I might also add that if you are planning to raise money following the release of good info, it does not hurt to have Dr.

[SPCEO1]

I do not know if my friend will ever update his call on TH on Fox Business channel but the appointment of Dr. Rothenberg is something he could mention that would likely be recieved well. You have the FDA giving the drug Fast Track status, Soleus taking the largest stake in the company and now Pfizer's CMO joining up at the same time the Chinese are looking to angle in early on TH-1902. It is a

[Wino115]

I guess I should have been clearer.  I've been trying to look at efficacy in the completely opposite direction since we know they have said nothing at this point.  In other words, if we try to prove it is ineffective within the confines of what data has been released then we can narrow down the issues causing that ineffectiveness a bit and assess the probabilities of those knowing

[palinc2000]

 If you combine that with their statement that from all they have seen it has been consistent with the preclinical work,  I have looked at the transcripts but could not find that statement but I do recall his statement during the CC but would like to read his exact words ,,,Do you remember in which part of the CC I should look again......I want to revisit thecontext 

[palinc2000]

This is the closest I found in the transripts  Paul Levesque 36:28 Thank you, Christian. It's got to be clear to everyone this morning that all of this is directionally correct. And quite frankly, we're very proud of where we are because it's a very least one point five times. The docetaxel that we're able to carry without significant side effects. So, we haven't

[Wino115]

I have heard that statement 3 or 4ti es now.  I recall one was Paul at one of the conf events.  I believe it may have been said in the KOL event too.  I would have to do a text search of the last 7 or 8 transcripts to see, but I have definitely heard it multiple times over the course of the dosage trial.  Sorry not to be more specific. Just haven't had the time to dig