Theratechnologies Inc T.TH

Updated time line

[jeffm34]

According to the clinical trial website the estimated completion date for the phase 1 trial was March 2022.

https://clinicaltrials.gov/ct2/show/NCT04706962

Now we know part 1 should likely be completed by March 2022. Almost 1 year after they started. Part 2 will involve more patients so we can assume it will take as long or more likely longer than part 1.  So now we are looking at least March 2023 to finish the phase 1 trial which means the trial is already a year behind schedule!

[longterm56]

I think I'll wait to hear from THTX, rather than assume the worst and create fictional schedules without any facts. "Fear, uncertainty, and doubt (often shortened to FUD) is a propaganda tactic used in sales, marketing, public relations, politics, polling and cults. FUD is generally a strategy to influence perception by disseminating negative and dubious or false information and a

[jfm1330]

Yes, this guy is posting messages with false content. That being said, phase Ia is taking longer than expected, that is clear, but it is false to assume that phase Ib will take as long. Phase Ib will not involve sequential dose escalation. In theory the planned 40 patients could be treated all at the same time with the same dose per body surface area (m2). It will not happen for practical reasons,

[jfm1330]

Again, we all knew they were slower than expected in the phase Ia, and now, maybe that reached a higher dose than really expected, or they reached their best case scenario which is three times the MTD of docetaxel alone. All that being said, nothing has changed on the communication timelines. In an article in the Montreal newspaper La Presse on October 13, it is stated this: "

[jeffm34]

I guess you don't know anything about clinical trials.  Just like last year when I said we wouldn't see any initial efficacy data from the phase 1 trial until first quarter 2022 at minimum.  You all said we would see some by the middle of 2021.   We are still at least a month (or 2) from part 2 starting. How long do you think it takes to enroll 40 patients?  Throw

[Wino115]

I think the oncology centers are generally separate type of facilities.  Some are only oncology centers, some are the oncology soecialization within a larger hospital system. While they can still have staffing issues, I don't think crowded ICUs are an issue for enrollment.  Just the normal Covid issues with patients and staffs.   Without guidance, any timeframe could be

[jeffm34]

It's 100% staffing issues right now.  Every facility is struggling to keep basic services open. 

[Wino115]

Right - seems most severe in midwest, FL and some New England parts right now.  Mid Atlantic a bit too.  Hopefully they will get Cedars Sinai in LA open as a center as that could probably fill half the quota of 1b right there given it's status and population center.   If we get lucky and the path is similar to South Africa, it should start fading in a month or so (although we

[scarlet1967]

    I think the pandemic has forced changes to  our ways to get things done. From increasing digital marketing to remote health care and conducting clinical trials among others. They are now suggesting decentralized trials so some information is exchanged through virtual communication and others by home visits. Obviously the pandemic will end at some point but

[Wino115]

Glad to know your 3 x vaccinated and kept it to just a mild flu. You're probably right. I guess viruses morph to try to live another day, so milder but more transmissable would be that path. Still hopeful a development like that in future strains and the Paxlovid will convince everyone you can go about your normal routines and just treat yourself with more assurance should one get it.  I

[scarlet1967]

Thanks, although early there are some not statistically significant news about omicron will replace Delta eventually I also read elsewhere the immunity in already infected patients with omicron increases the immunity against delta!   https://www.reuters.com/business/healthcare-pharmaceuticals/safrica-study-suggests-omicron-enhances-neutralizing-immunity-against-delta-2021-12-28/  

[pantonorr]

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