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Bullboard - Stock Discussion Forum Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs... see more

TSX:TH - Post Discussion

Theratechnologies Inc > New article about Sort1 targeting PDC/potentially PDCs
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Post by scarlet1967 on Aug 04, 2024 3:44pm

New article about Sort1 targeting PDC/potentially PDCs

 

I don't have access to the full article. But what they are talking about in the parts of their study available to public all has been discussed here many times including the reference to potentials for other peptide drug conjugates using other anti cancer drugs(warheads) among others!!

A bit of exposure and recognition in China is definitely useful..

 

"Highlights

The novel TH19P01-camptothecin (CPT) conjugates were designed, efficiently synthesized, and evaluated for their anticancer potential.

The hybrid peptide LYJ-2 could quickly enter the SORT1 high-expressed cancer cells, the efficiency of which was significantly higher than that of free CPT.

LYJ-2 exhibited selective anti-proliferative and anti-migration effects against SORT1-positive cancer cells.

Through conjugating with TH19P01, both the water solubility and anticancer selectivity of CPT could be significantly improved.

The TH19P01-CPT based hybrid peptides hold potential for the further development of promising PDCs against SORT1 high-expressed cancer cells."

https://www.sciencedirect.com/science/article/abs/pii/S0968089624002839?via%3Dihub

Comment by Trogarzon on Aug 05, 2024 9:34am
Great... I feel much better now....
Comment by Trogarzon on Aug 07, 2024 6:32pm
Wonder if they can keep this dam thing above 1$ or 50m market cap to avoid further humiliation.
Comment by Trogarzon on Aug 07, 2024 6:56pm
 But some efforts must be put into that.  Even with the 60m dept considering the 80m+ sales, it's lousy job ovethere.
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