Post by
beechguy on Jul 30, 2014 12:09pm
Peak Sales of MCNA and potential.
I don't buy for a second that 200-400mm is peak sales for MCNA. There are 80,000 new cases (along with likely 100s of thousands in current patients) in NA alone each year. 80% of them are NMIBC of which around 55% become refractory to BCG (current SOC). Their only choice is cystectomy (bladder removal along with Ostomy). So 80k x 80% x 55% give you 35,200 patients refractory to BCG. Lets assume a 50% market share (likely much higher as bladder removal is next step) . At a 35k price point (Provenge for refractory PC is 93,000) that is $616,000,000. With EU you can double those figures to 1.23B. I know a Urologist that refuses to administer BCG because of its toxicity and the need for a separate haz mat lab to administer it. There will be lots of off label. First line trial in phase 1 had a CRR of around 70%. So it is extremely effective in front line use. It is easy to forsee peak sales in the 1B to 1.5B range depending upon insurance coverage. Considering it is the most expensive cancer per patient of them all, that should not be an issue. They also have a post chemo adjuvant that gets white blood cell counts back to normal within 48 hours of chemotherapy. This is a multiple billion application for all cancers. This is the one that may really entice a buyout from suitors. Just my 2 cents. Buy now and buy often. .30s is so undervalued....$1 dollar is undervalued. No brainer at these levels. When someone big finally figures this out and the dummies selling pull their offers, this thing will run like we've never seen it before! GLTA beech
Comment by
IoftheLynchMob on Jul 30, 2014 3:58pm
Was frustrated, now as pleased as can be. The previous group of managers would not or could not seem to to get anywhere near a submission package. Had they it would have more than likely been botched in one form or another and we would still be dealing with the ongoing shortcomings that were the hallmark of Bioniche until very recently.
Comment by
winx08 on Jul 30, 2014 3:59pm
RetailRube, you write: Bioniche likely is continuing to collect data on whether/when the cancer came back for those people treated during P3a. I am not 100% sure, but as i recollect it is mandatory to continue monitoring patients. For how long ? I will enquire about his next week (i know a guy who should know but he is out in algonquin) cheers winx.