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Bullboard - Stock Discussion Forum Ceapro Inc V.CZO

Ceapro Inc. is a Canada-based biotechnology company. The Company is involved in the development of extraction technology and the application of this technology to the production of extracts and active ingredients from oats and other renewable plant resources. Its primary business activities relate to the development and commercialization of natural products for personal care, cosmetic, human... see more

TSXV:CZO - Post Discussion

Ceapro Inc > Blood vessel damage
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Post by prophetoffactz on Oct 31, 2022 7:30am

Blood vessel damage

 
UK Cardiologist Rae Duncan explains Long COVID beautifully.

Abnormal, prolonged immune response damages the inner lining of blood vessels.

Micro clots form, of abnormal molecular structure, that the body’s usual mechanisms can’t get rid of. They show up in various organs.
Comment by Ciao on Oct 31, 2022 9:27am
Over a year of preclinical in vivo studies by the Angiogenesis Foundation, so should we expect Phase 1 studies to begin sometime in 2023? "the Angiogenesis Foundation will be conducted to characterize the in vivo bioactivity of Ceapro’s oat-derived bioactive products, beta glucan and avenanthramides, on angiogenesis, blood vessels repair, wound healing and tissue regeneration." ...more  
Comment by prophetoffactz on Oct 31, 2022 9:43am
The Angiogenesis Foundation was studying avenanthramide. CZO's avenanthramide clinical trial is expected to get the 'green light' from Health Canada imminently. Gilles has previously said he hoped to include a trial arm for COVID heart inflammation. Perhaps COVID blood vessel damage could also be studied. Blood vessel damage is also important in cardiovascular disease which has been ...more  
Comment by Ciao on Oct 31, 2022 10:30am
MHI Phase 1 AV study go ahead must have been based on their previous work with University of Minnesota on exercise induced inflammation as well as Ceapro's own in vitro studies. Without results from the Angiogenesis study which was to look at BG and AV, what input did the Angiogenesis Foundation work have in the design of the Phase 1 AV study to be conducted by MHI? The public hasn't been ...more  
Comment by prophetoffactz on Oct 31, 2022 11:21am
"MHI Phase 1 AV study go ahead must have been based on their previous work with University of Minnesota on exercise induced inflammation as well as Ceapro's own in vitro studies." Avenanthramide has already been studied in human trials and that data has been used to support the trial application Gilles has said. I believe CZO has selected key parts of avenanthramide and created a ...more  
Comment by prophetoffactz on Oct 31, 2022 11:28am
CZO is also studying avenanthramide for metabolic disorders in the proposed study. This research was recently released: "Based on our results, we have confirmed for the first time that the glucose uptake is indeed inhibited by the presence of avenanthramides, suggesting the possibility of incorporating avenanthramides in foods to enhance postprandial glucose response, and ultimately improve ...more  
Comment by prophetoffactz on Oct 31, 2022 11:37am
Free Radic Biol Med         . 2008 Feb 1;44(3):415-29.  doi: 10.1016/j.freeradbiomed.2007.10.036. Epub 2007 Oct 22. Avenanthramides, polyphenols from oats, inhibit IL-1beta-induced NF-kappaB activation in endothelial cells  ...more  
Comment by prophetoffactz on Oct 31, 2022 12:11pm
"...almost half of heart attacks and strokes in the United States occurred in people who did not have high cholesterol." "The idea that cardiovascular disease is an inflammatory condition is broadly accepted today. In the past several years, a handful of large clinical trials has refined the understanding of the pathways involved and brought new anti-inflammatory therapies for ...more  
Comment by prophetoffactz on Oct 31, 2022 1:03pm
 “My belief is that the sum will be greater than the parts. If we could figure out an inexpensive, safe way to dramatically lower cholesterol and dramatically lower inflammation earlier in life, maybe we could actually eliminate this disease.” So the question: Can avenanthramide play a role? In addition to treating inflammation CZO's avenanthramide may also help heal blood vessels. It ...more  
Comment by Ciao on Nov 01, 2022 1:13pm
Ceapro has a monopoly based on their ability to extract and refine AV to the purest form. Let's see when the Phase 1 study with MHI will start. AV could have promise in other areas as well, even cancer, but we're getting ahead of ourselves here. AVAs are able to modulate several events, such as apoptosis, cell proliferation, metastatization, specifically involved in all stages of cancer ...more  
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