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Bullboard - Stock Discussion Forum Ceapro Inc V.CZO

Ceapro Inc. is a Canada-based biotechnology company. The Company is involved in the development of extraction technology and the application of this technology to the production of extracts and active ingredients from oats and other renewable plant resources. Its primary business activities relate to the development and commercialization of natural products for personal care, cosmetic, human... see more

TSXV:CZO - Post Discussion

Ceapro Inc > wound dressings - next stage?
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Post by Ciao on Nov 06, 2022 7:44pm

wound dressings - next stage?

This article provides an overview of current offerings of wound dressings with bioactives;

https://www.mdpi.com/2076-3417/11/9/4114/htm

Alginate as a substrate appears to have some advantages for treating exuding wounds and curcumin which is an anti-inflammatory is commonly noted in dressings.  Ceapro has demonstarted improved healing in animal models on burn wounds when controls are compared to PGX-alginate/calcium and further improvement when ibuprofen is added (ref. HCW webcast in May, 2022).

The study itself was mentioned in a 2020 published paper (https://www.sciencedirect.com/science/article/abs/pii/S1742706120303275)/

"The impregnated scaffolds significantly accelerated burn wound healing while also promoting regeneration of the native skin morphology. We anticipate this approach can be leveraged to load clinically-relevant and highly bioavailable dosages of hydrophobic drugs in hydrogels for a broad range of potential applications."

It would be interesting to know how much more work has been done since and what the next steps are; is it ready for licensing?
Comment by Ciao on Nov 06, 2022 7:53pm
"While medicated hydrogel-based wound dressings offer clear advantages in accelerating wound healing, the inherent incompatibility between conventional hydrogels and many poorly water-soluble drugs of relevance in wound healing remains a challenge. " With the recent positive PGX alginate CoQ10 bioavailability study results from the University of Alberta, the solubility of bioactives in ...more  
Comment by Ciao on Nov 07, 2022 1:58pm
The TAM for wound dressing is expected to have a CAGR of 9.7% so that the global market would be over $11B USD by 2025. https://www.marketsandmarkets.com/Market-Reports/wound-dressings-market-123903496.html?gclid=CjwKCAiA9qKbBhAzEiwAS4yeDWkzM25V8zGIIx2eL64LQc8uvdmyhPcjMYcotqfw5nylCxpsSRRd0xoCVjgQAvD_BwE I would be interested to see quickly we could get a partner as this would be a lucrative ...more  
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