Ceapro Inc V.CZO

CZO put this section in bold...

[prophetoffactz]

CZO put the section on its fibrosis drug in bold lettering as if to draw attention to it and notes an "important finding":

  Yeast Beta Glucan (YBG) - Potential Inhalo-Therapeutic

• "Following the announcement of encouraging results made at two major international conferences earlier this year demonstrating that PGX-YBG is respirable and able to safely and reliably reprogram macrophages in the lungs in pre-clinical mouse models, additional research at McMaster University clearly showed that PGX-YBG gets into the macrophage cell. This important finding further supports the potential of YBG to act as a stand-alone and/or a carrier for other bioactives when transported by macrophages cells."

By making an "important finding" that PGX-YBG can clearly get into macrophages has Gilles made another important breakthrough? Has Gilles discovered a way to hijack macrophages and deliver bioactive throughout the body to remote sites as a booster rocket to PGX carrier delivery? Is that what explains the blowout CoQ10 bioavailability results vs. the industry gold standard CZO has produced? What other companies can acheive this with their CoQ10 carriers in what Gilles said was a $4 billion market? At the AGM Gilles said it was in talks with serious companies that understand bioavailability as a unique selling point. 

Trojan Horse:

• "Of interest, the size of PGX processed YBG particles (around 5 microns) would allow them to be “swallowable” by macrophages that would carry them to remote sites in the body. Thus, the loading of drugs onto PGX YBG is currently under further investigation, since numerous research studies suggest that YBG cells being swallowed by macrophages could be utilized as “Trojan Horses” to carry bioactives (potentially CoQ10, antioxidants, pain killers or potent pharmaceutical drugs) into the body to the target tissue." Aug. 24, 2022 CZO news release

[prophetoffactz]

Int J Nanomedicine. 2023; 18: 4521–4539. Published online 2023 Aug 8. doi: 10.2147/IJN.S421173 PMCID: PMC10422973 PMID: 37576466 Macrophages as Promising Carriers for Nanoparticle Delivery in Anticancer Therapy Anna Wrblewska,1 Agnieszka Szczygie,1 Boena Szermer-Olearnik,1 and Elbieta Pajtasz