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Destroying Cancer at the Speed of Light®

Clinical Study Underway (75 of 100 Patients Treated)
Expected to complete enrollment at the end of 2024
Expected to complete study at the end of 2026


Bullboard - Investor Discussion Forum Theralase Technologies Inc. V.TLT

Alternate Symbol(s):  TLTFF

Theralase Technologies Inc. is a Canada-based clinical-stage pharmaceutical company. The Company is engaged in the research and development of light activated compounds and their associated drug formulations. The Company operates through two divisions: Anti-Cancer Therapy (ACT) and Cool Laser Therapy (CLT). The Anti-Cancer Therapy division develops patented, and patent pending drugs, called... see more

TSXV:TLT - Post Discussion

Theralase Technologies Inc. > Non optimized vs optimized
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Post by enriquesuave on Sep 05, 2021 2:16pm

Non optimized vs optimized

1st 12 patients undertreated by 39-85% yielded a 25% CR  or 3 patients at 90 days 
6 optimized treated patients yielded 67% or 4 out of 6 patients and maybe would have been 5 as one patient died after negative urinate cytology.  

 Hence Optimized is about 2-4 Times as likely to get CR at 90 days.  IMO

Comment by Oilminerdeluxe on Sep 05, 2021 2:34pm
If we get a solid update next time around (mid December?), I suspect that many on the sidelines will jump in hard. I know I will scramble together a pile of coins for when the time is here. The numbers will be too good to be ignored if the majority of those pending are healthy. Well, that is what my warped mind thinks anyway.
Comment by Eoganacht on Sep 05, 2021 5:12pm
Very encouraging. 25% of the first 12 underdosed patients were CR at 90 days. Keytruda only achieved 41% at 90 days and just 19% at one year and this was enough for FDA approval. At a bare minimum TLD1433 will achieve twice this number of CR patients and likely many more than that. It's looking very good for FDA approval and very significant stock price appreciation.
Comment by enriquesuave on Sep 06, 2021 2:31pm
To be more thorough, to date 27 patients have been treated at a therapeutic dose ( high dose of drug).  Of those 13 have had a non-optimized treatment procedure  (patient #4 from PH1 and 1st 12 treated patients from PH2.  The remaining 14 patients in total have received an Optimized Treatment  Procedure ( patients # 5 & 6 fro PH1 and patients #13-24 from PH2).  Non ...more  
Comment by Oilminerdeluxe on Sep 06, 2021 2:55pm
Thank you, Enrique. You write those numbers so well even a grumpy sod like me understands it a whole lot better than when trying to read the news releases. If the next update contains, say 5 patients, where a strong majority is healthy, then I think everyone will be very happy. Perhaps not an automatic rerating of the share price will follow, but it should then only be a matter of repeating ...more  
Comment by tdon1229 on Sep 06, 2021 10:31pm
  Always remember that Murphy was an optimist.
Comment by Oilminerdeluxe on Sep 07, 2021 12:07am
A pessimist says. "It can't get any worse than this" An optmist says. "Yes it can!" Makes med feel happy the board is much happier again. Hope it continues.
Comment by Johnandrose22 on Sep 06, 2021 3:00pm
It remains, for me, a testament to the brilliance of this company’s clinical staff to offer Ph.1 patient’s 5 and 6,via their optimized protocol, a new lease on their lives. It remains, for me, equally disturbing why Ph.2 patients 1-12 were not afforded that same opportunity. In the end, let us all hope and pray that all will be well. John
Comment by Eoganacht on Sep 06, 2021 3:19pm
Great analysis. Currently 75% CR at 90 days for the optimized patients. And there is still the possibilty of a maximum 86% CR rate at 90 days for the current optimized patients. Exactly the sort of results many expected when the phase 2 trial started. And this is just the beginning. There are another 76 patients coming who will receive 2 optimized treatments who will bring up the overall CR rate ...more  
Comment by Yajne on Sep 06, 2021 4:59pm
Thanks enrique and Eogan. Also mentioned in corp presentation was that to date there are 3 treated in the US. That seems low and I would expect the rate to pick up in the US given the type of clinical sites chosen in US. Let's hope that the optimized treatment protocol is executed consistently at all US sites. 
Comment by blackjack0 on Sep 06, 2021 6:32pm
I have a question about the non optimized patients who received the optimized treatment as their second treatment. Is there any data as yet on how they made out. That should soon be starting to come out 
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The Road to Saving Lives: Clinical Study Underway

  • Clinical Study with 75 of 100 Patients Treated (Enrollment to be completed by end of 2024, with study completed by end of 2026)
     
  • Ground Floor Investment Opportunity in Multi-Billion Dollar Industry
     
  • Best-in-class treatment for NMIBC (according to interim clinical data)
     
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The Road to Saving Lives: Clinical Study Underway

  • Clinical Study with 72 of 100 Patients Treated (Enrollment to be completed by end of 2024, with study completed by end of 2026)
     
  • Ground Floor Investment Opportunity in Multi-Billion Dollar Industry
     
  • Best-in-class treatment for NMIBC (according to interim clinical data)
     
  • NMIBC (Non-Muscle-Invasive Bladder Cancer)
     

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Address:
41 Hollinger Road
Toronto, ON M4B 3G4
Canada

Toll Free:
1-866-THE-LASE (843-5273)
Local Phone:
416-699-LASE (5273)

Email:
info@theralase.com

Fax:
416-699-5250