Theralase Technologies Inc. V.TLT

Crutial 450 day data.

[wildbird1]

The 18 optimized patients 450 day data are crutial for the BTD application in Dec 22. Let's see why.

First what we know.
-In Dec 22, 18 optimized patients will have completed their 450 day data.
-In Dec 22, TLT will submit data on 20-25 patients for BTD application.
-The treatment protocol that has been approved by the FDA, is the "Optimized Treatment Protocol".
- With the "Optimized Treatment Protocol" approved by the FDA, we can easily assume that the 18 optimized patients 450 day data will be the first data that will be included in the 20-25 patients data that TLT will submit to the FDA for BTD approval.
-From the 1Q2021 Newsletter, we know that once a patients has obtained a CR(Complete Response), the duration of the response remain fairly durable(Approximately the same at 180,270,360 day...etc).

1) 18 Optimized patients CR%.
From the 3Q2021 Newsletter, we know that the 90 day CR% on 11 optimized patients(18-7 pending=11 patients) is 8CR/11patients=73% CR.
Let's extrapolate for 18 optimized patients, 18x73%=13 CR patients/18 patients.

2) From the 3 patients in the Phase 1b Study...(included by TLT in the phase 11 study data) we have 2CR patients.

3) From the 12 undertreated patients we have 3CR patients(25%).

Remember once a patients get a CR, the duration of the response remain fairly the same.
Dec 22, 20-25 patients CR%.
The 20-25 patients data that will be submited to the FDA in Dec 22,could be as follow.
13 CR patients(from the 18 optimized).
+5 remaining patients (from the 18 optimized).
+2 CR patients (from the Phase1b study).
+1NR patient (from the Phase 1b study).
+3 CR patients (from the 12 undertreated).
+1 NR patients (from the 12 undertreated).
Grand total 25 patients.
18 CR patients/ 25 patients= 73%CR in Dec 22.

All the above could explain why Dr.Arkady Mandel, in a June 24,2022 PressRelease said " The success in the Phase 1b NMIBC clinical study, has led to the impressive preliminary results demonstrated in the Phase 11 NMIBC clinical study".

Note: Dr.Mandel gave us a big clue when he said " has led to" indicating that these impressive preliminary results are genuine, and only need to be compiled and certified in Dec 22.

Dec 22.
Very soon.

[Oilminerdeluxe]

Nice numbers indeed. Hope they come true.

[Yoly900]

This post has been removed in accordance with Community Policy

[Tapps21]

Great post Wildbird! Very encouraging and let's hope the FDA sees the numbers as favourable as we all do. 

[N0taP00p]

Thank you, Wildbird for taking the time. Can you or others elaborate a bit on the assumption behind duration of response staying the same? Are you saying once a patient is CR, that patient is likely to maintain CR at future checkpoints? With these 3 cohorts in the data, it can be a little confusing. Also, how much value will the FDA assign to PRs?

[DJDawg]

Can't speak to all you are asking. The very first 1b patients treated properly were CR for 2 of the 3 patients. They have been followed for years after that one treatment and stayed CR. The competitor, immunotherapy, is often like whack a mole. Hoping that the immune system willl attack the cancer cells and kill enough that there are no survivors. Given enough time if any cells still

[N0taP00p]

Thank you, DJDawg and Robershaw. There is so much to cheer and hope for, yet, this persistent fear driven by the cheap fund raises and inconsistent communications. Why a company apparently so close to FDA approval for a long awaited non-BCG treatment is still at 25 cents is beyond me. And that's not even counting all the other bullets everyone says they have for Covid, NSCLC, etc. Plus, you

[robertshaw]

Yes, once the patients passed 180 days cancer free, most probably the patients would get 270,360 days cancer free. I still remember the day that the 5th patient of Ph1b get his 270 days, I predicted we should get his 360 days cancer free results also, but Blowjobjoe doubted my prediction and wanted to make a bet with me. Soon, when the day on Jan. 30th, 2019. PMH announced the news of the 5th

[Yoly900]

Failure fk us in the bud hole no Vaseline son chrissy pusy fire Putin come in for yu

[Yoly900]

0.00000111111 by holidays mfs roger is gonna fk Arkady with a 12 ft pipe that the JV WEERE WSITIBG FIR 

[Camphikefish]

robertshaw, thank you for this post and your contributions. Please allow me to ask you and every one else here who have stated BJJ and a few others work hard each day to manipulate Theralase stock. How in the world and why on earth would anyone dedicate so much time manipulating such a low volume stock? Is it not correct to say if you aspire to hold prices down for any given stock there would be

[Legit62]

Agree with you Camphikefish, not enough shares to make money manipulating. Its a Canadian penny stock company waiting to further their cause with new data soon, possibly by end of month, then we should have a better vision on where we are heading, whether someone likes what we got and buys us out or partners or they make the move on their own which i doubt, the ages of those in charge i think will

[Yoly900]

This post has been removed in accordance with Community Policy

[Yoly900]

You guys ases I got rid of this pos long ago 

[greaterfoolFred]

Yes, nice numbers wildbird, but I dont think you can just drop the 5 NRs from the undertreated 12.  Any trial would work out with nice numbers if you could drop the NRs and just keep the CRs.  If you want to drop those 5, you have to drop all 12, which is what we should do. Of course you can't just hide them from the FDA, but we should submit 25 optimized patients' data; worth

[stocksnbonds458]

I have been railing against this manipulation nonsense for years. TLT has been trading within the same range almost from inception, the posts from the conspiracy theorists and uniformed turns this site into a rather large bore. I have most all of these knuckleheads on ignore thankfully, but some still sneak through the firewall lol. I have great hope for the company, but with nearly 300M shares

[robertshaw]

https://www.otcshortreport.com/company/TLTFF Check the above link, and ask yourself, why Blowjobjoe's bosses naked even 200 shares, they short this technology not for profit...

[Camphikefish]

Thank you robertshaw. And so given that they naked short and we know its not for profit, why then do they do this: 1. To hold the price down artificially? 2. To make the technology seem illegitimate? 3. To create a buying opportunity? If these things are possible reasons then there must be answers and I only seek WHY since we always seem to discuss manipulation. If not for current or future profit

[99942Apophis]

Camphikefish for what you're asking would involve one to relate to you multiple variations of instances in market trades or Option trades. The best direction for you at this point would be to get yourself a few good financial books at a local bookstore read and make notes in each book, devote minimum of 1 full hour a day. After a year of learning from the books consider your next step of

[Yoly900]

This garbage company will never ever go up for the fact no one gives a flying fk. They're loosers s squeezed corporation at their finest pure garbage

[Yoly900]

There is no communication otherwise they'll get caught at their scam I got sure know what they are doing isuing stocks warrants mfs scmbgs pos husband wife and 2.00 doctor thsts only thing worth 2.00 is him . The sec will inspect these mf morons I've gone to them explained this bulkshite trading every fkn day and left us in dark since 10 years of scamming new money. They was I'll pay

[robertshaw]

By manipulating the share price to dirty low level all these years, Blowjobjoe's bosses can thus starve this technology from getting more fund (such as several former PP's warranties were forced to abortion). Blowjobjoe's bosses thus get huge commission fee and bonous from big pharmaceutical companies, that's why they naked shorting not for profit.

[Camphikefish]

Thank you very much robertshaw for explaining this. I now fully understand their motive, method, angle, parties involved and whats in it for them. I get it now. All of this I gathered from your helpful answer and I did not have to study an hour a day for a year and then enroll in a year long investing class. Good grief is all I can say about the other response I received. What a peculiar response

[wildbird1]

greaterfoolfred said, Wildbird you can not use the 4 undertreated patients (3CR+1NR) in your post. Ok, let's get rid of the 4 undertreated patients in my post. 25 patients - 4 undertreated = 21 patients left(which is in the rage of the 20-25 patients required by the FDA). 15CR/21 patients = 72%CR. Even better let's replace in my post these 4 undertreated patients(3CR+1NR) by 4NR

[Yoly900]

Chrissy phone home. Arkadymanscammmmm

[Yoly900]

Pos stock same shite this week next next etcc  total bullshite fk numbers I hope we go bust soon this is fikn torture SEC ON WAY MFS

[ScienceFirst]

Wildbird1 ... Nice post.  Thanks for adding your vision. And thanks for this refresher: All the above could explain why Dr.Arkady Mandel, in a June 24,2022 PressRelease said " The success in the Phase 1b NMIBC clinical study, has led to the impressive preliminary results demonstrated in the Phase II NMIBC clinical study". Note: Dr.Mandel gave us a big clue when he said