Theralase Technologies Inc. V.TLT

Fine-Tuning = 72%.

[wildbird1]

If like me you have difficulty to understand the data, just keep in mind one thing, with each update the data are getting better and better.
Yes, getting FDA approval is a slow process, and TLT is slow, or shall we say TLT is very carefull not to over do it.

Although we would like the process to go faster, fast is not always a good idea.
Look at ImmunityBio, they received BTD for N-803+BCG, and they had better results than TLT, now the FDA has stopped the approval process, because of manufacturing issue. It could be years before N-803+BCG approval.
Nobody want TLT to rush into such a mess.

Dr.Kulkarni & 72% Fine-Tuning.
One very important quote that went unnoticed in the last video by Ashish Kamat & Dr.Girish Kulkarni(provided by livermore2).
Dr.Kulkarni said" So there is a learning curve to it. With any new procedure, it will take time to learn that. But now we've got it down to a "fine art".

In short, what Dr.Kulkarni is saying, we at TLT are getting damn good at fine-tuning this treatment. If Dr.Kulkarni " fine art" quote is veracious, we should see the result of this "fine-tuning" in the last Swimmer Plot with the last 14 evaluable patients treated.

10/14 Patients are CR(green dot) 72%CR.
  2/14 Patients are IR(yellow dot)   15%IR.
TR(total response) 72%+15%= 87% TR.
Ok..these numbers will change, but for now, could we agree that 72% CR is a very good proof that Dr.kulkarni "fine-tuning art" is working great.

This 72%CR "fine -tuning" mean that the number of red dot will stabelize, while the number of green dot will increase steadily.
Note: In the last Swimmer Plot , of the last 14 evaluable patients treated, only 2 are red dot, given time the total number of green dot could surpass the red dot.

For now, we have to sit tight and let the process run its course.

That is what I am going to do.
For the next few weeks, me and a group of friends are going to try "fine-tuning" our golf swing :).

Have a nice summer everybody.

[N0taP00p]

@wildbird1 - how can your CR number be more than twice that published by Theralase. Even the KM curve projection doesn't cross 35% at 450 days.  

[Eoganacht]

wildbird is not writing about the CR rate at 450 days - he's writing about the CR results of the 3 patients at 270 days, the 7 at 180 days and the 4 at 90 days. 10 out of these 14 patients are CR - that's 71% You have to look at the recent swimmer's plot to appreciate what he's saying. The results at 270 days and below are predominantly CR.

[N0taP00p]

Thank you, Eoganacht. Appreciate the clarification. So the 450 day CR should only get better in about 6 months or so. 

[Eoganacht]

IMHO in 3 months the 450 day CR rate should be 36% and in 6 months it should be 41%

[Donein25]

On top of that, if my math is correct...currently 91% of those with CR at 360 days continue as CR at 450 days.

[DJDawg]

Or if you look at those with an unbroken streak of CR from 90 to 360. 100% keep it.