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Destroying Cancer at the Speed of Light®

Clinical Study Underway (75 of 100 Patients Treated)
Expected to complete enrollment at the end of 2024
Expected to complete study at the end of 2026


Bullboard - Investor Discussion Forum Theralase Technologies Inc. V.TLT

Alternate Symbol(s):  TLTFF

Theralase Technologies Inc. is a Canada-based clinical-stage pharmaceutical company. The Company is engaged in the research and development of light activated compounds and their associated drug formulations. The Company operates through two divisions: Anti-Cancer Therapy (ACT) and Cool Laser Therapy (CLT). The Anti-Cancer Therapy division develops patented, and patent pending drugs, called... see more

TSXV:TLT - Post Discussion

Theralase Technologies Inc. > Next week's trial result update
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Post by Eoganacht on Aug 21, 2023 12:43pm

Next week's trial result update

Next week we should get an update on the trial results. The last one we got was on May 30 and looked like this:

CR 90 days CR 180 days CR 270 days CR 360 days
60% 53% 43% 36%
32 out of 53 26 out of 49 18 out of 42 14 out of 39

The CR rate at 450 days (33%) won't likely change as there weren't any patients diplayed on the swimmer's plot at 360 days waiting for their 450 day evaluation. Here is the best case scenario we could see next week. This assumes that all of the 5 patients waiting for their 90 day evaluation are CR.

CR 90 days CR 180 days CR 270 days CR 360 days
64% 53% 49% 38%
37 out of 58 28 out of 53 24 out of 49 16 out of 42

We will have to wait a while to see a big improvement in the 450 day results: The May 30 results looked like this:

CR 450 days
33%
13 out of 39


In 6 months, if all goes well. the 450 day results could look like this:

CR 450 days
41%
20 out of 49
Comment by Eoganacht on Aug 21, 2023 12:53pm
It looks like we are headed for a 450 day CR rate of around 40% in 6 months. Is it possible Theralase is waiting for this result before submitting their BTD application - so as to remove all doubt about durable complete response? 
Comment by Legit62 on Aug 21, 2023 1:04pm
The question then remains Eoganacht whats more needed to get BTD and AA with this phenominal data??
Comment by charlierock on Aug 21, 2023 1:16pm
I'm looking forward to the next update. It appears to be the most promising and eventually the best treatment available as each update verifies the continued improvement in the data plus the lack of negative side effects and treatment being done on a outpatient basis. However management needs to convey to us shareholders the status of a BTD application which was supposed to happen  in ...more  
Comment by N0taP00p on Aug 21, 2023 1:27pm
Thank you for keeping it sane around here with summary data and feasible projections, Eoganacht.  I'm hoping that the collective hope that is riding on "next week, next NR, next month, next quarter, after AUA, after AGM" , etc. is soon going to be history.  In a good way.  If they indeed applied for BTD right after the AGM, we should hear back in a few weeks. Even ...more  
Comment by 99942Apophis on Aug 21, 2023 2:07pm
Good chance we'll see 450 days between 40.5%  - 42.8%  I keep looking over my should for the police to arrest me for buying shares & warrants at such great prices, I haven't been this happy since I won the lottery. 
Comment by enriquesuave on Aug 21, 2023 1:45pm
Nice post!  If we can at least maintain results or show a slight improvement, then we are golden.  IMHO.
Comment by FGPstock on Aug 21, 2023 2:21pm
  Ego, you definitely do your homework and add a lot of insight. But why do you feel Tlt would b in the middle of a pp if they were about to announce great numbers. Being the 21st, I am pretty sure they should already have the data in hand
Comment by Eoganacht on Aug 21, 2023 2:45pm
I don't know FGPstock. My guess would be that they don't have any serious bites from big pharma yet and I would attribute that to the fact that Theralase is breaking new ground. Big pharmas may be slow to change direction given all the money they have coming in with their current pipelines. How many anti-cancer photodynamic therapies is big pharma currently involved in? I believe that at ...more  
Comment by FGPstock on Aug 21, 2023 3:00pm
Agree that fantastic clinical data would bring in new investors. Just doesn't make sense to do a PP on the cusp of such news and practically speaking, if they already have the data and are doing a PP, per Roger, it seems like it may cause a conflict of interest as typically, management invests in its own PP's.
Comment by Eoganacht on Aug 21, 2023 3:28pm
I think we already have fantastic clinical data and so far there's been no news about alternate sources of financing. Next week's news should be only a little bit better, as is clear from the May 30 swimmer's plot. But in 6 months time I'm hoping the news will be substantially better.
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  • Ground Floor Investment Opportunity in Multi-Billion Dollar Industry
     
  • Best-in-class treatment for NMIBC (according to interim clinical data)
     
  • NMIBC (Non-Muscle-Invasive Bladder Cancer)
     

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