Post by
Rumpl3StiltSkin on Oct 24, 2023 6:25pm
Good discussion boys
It definetly jogged my memory on What's necessary for BTD and AA submission.
Comment by
Rumpl3StiltSkin on Oct 24, 2023 6:29pm
It has always been 20-25 patient data at 450 days for this study 2. So has this changed? For either BTD or AA? If not then the cohorts BF, FGP and Poop, are they all the same person? Are full of it. TLT has this data whether looking at the old data or the optimized data. So.....
Comment by
DJDawg on Oct 24, 2023 8:21pm
I think that 20-25 patient data threshold is out of date. I believe that when they had the 2/3 CR's in the phase 1b they were told that IF the data continues to look this good over time then 25 patients would be sufficient. 66% CR carried forward to 450 days would be good enough. Then came the undertreated patients and the CR's changed so all bets were off.
Comment by
Johnandrose22 on Oct 24, 2023 8:38pm
I will be keenly focused on the company's next NR...no matter how significant/insignificant the headline might be. I will be reading every word, every letter in the commentaries of Dr. Mandel and Mr. White regarding the status of this company. 2024 will mark 10 years for me without a dime of return....I'm getting tired. John
Comment by
Infinity on Oct 24, 2023 9:03pm
John and Rose, I get it, I am with you on this. It has been nearly 10 years for me as well. I first got interested in 2013 after a run-in with Dr. Jewet at PMH.
Comment by
Pandora on Oct 24, 2023 9:56pm
As they say --- you're not alone!
Comment by
Donein25 on Oct 27, 2023 9:17pm
No one here cares what you say Buddy boy. No one. Good bye Foxx.
Comment by
O12009 on Oct 27, 2023 8:17pm
The only way I see the id--- post is you make it a discussion instead of a comment ,please put him on ignore. thanks
Comment by
Rumpl3StiltSkin on Oct 24, 2023 9:20pm
Let's be clear here, they now have 40% CR+IR optimized patient data on 33 patients. @ 450days. They can submit BTD as soon as they have the data FDA requested. Which they may have at this time.38% CR+IR Dara @450 days on the non optimized group of ~40 patients. Pretty good %s and significantly better than keytruda. Ruvdar has few side effects and is a monmo treatment.
Comment by
Oilminerdeluxe on Oct 28, 2023 3:26am
We should have some money soon then. Any idea how much a GBM study might cost? I assume it will be a while until it happens. Lets just hope that freaking financing gets filled. I find it odd it went so muuh lower than the financing price, but it should bounce back once closed one would think
Comment by
Rumpl3StiltSkin on Oct 28, 2023 10:00am
TLT just got a. Canabinoid patent. I'm guessing they want to use that for a GBM phase 1? Do they have a Cannabis company in mind to partner with? Many Cannabis companies are flush with cash and would love to branch into medical. A small Canada based phase 1 might not cost that much and will allow them to dive into the world of solid tumors. IMO.