Theralase Technologies Inc. V.TLT

Complete Response Rate at 450 Days 28.6% ?

[Eoganacht]

In the news release it says the 450 day CR rate is 26.5%

This rate represents the 18 out of 68 patients who are CR at 450 days.

But 5 of those 68 patients have not yet reached 450 days so isn't the current CR rate at 450 days actually more like 18 out of 63 patients or 28.6% ?

[enriquesuave]

I believe you are correct!  They are putting out Cr percentages out of full 68 patients even at 3 years.  Obviously these percentages will go up as more patients reach the time frames!  These are the lowest minimum possible CR rates if all other patients would not be CR at the stated time points.  They are being ultra conservative IMHO.    

[CancerSlayer]

That's how I see it.  Using our interpretation, TR patients (CR + IR = 72.1%) who had a durable response would also be understated....we would have 19 of 63 patients, or 30%.  The NR also states that the TR patients (reported as 19/68 = 27.9%) had a "duration" of this response for at least "450" days.  However, I believe the response duration (90 to 450 days)

[TommyNickels]

I believe the study is designed to report 360 days after the first examination (at 90 days). So 450 days in total. Hopefully the FDA says 75 patients is sufficient.