Vaxil Bio Ltd V.VXL

Oral 💊 is the game changer !!!

[bligicka]

Without oral Vaxil is just another potential vaccine that doesn't even have phase 1 timelines ......nobody will care ... with oral they have an opportunity to make a real difference in the world

[Padina]

Blig, dont get it twisted. Peptide is the unique selling point here. Its superior safety profile, robustness of immune & T-cell response & its ressistance to virus mutation. What is more, VXL is the only company that subjected its discovery to a virus challenge - This is a critical step that all other vaccines omitted. So if a vaccine passes a virus challenge, are you telling us that

[Jlane17]

I'm sorry Padina but they are not the only company to submit a challenge. I don't think you have a understanding of the difference between an oral application and a vaccine that requires shots in your arm. A positive result would be great in the mice experiment, what would even be better is they can generate a immune response with the oral application. 

[bligicka]

Thats the news I'm looking for .... a immune response with the oral application ... that is the true game changer  !!!!.... lots of vaccines out there now but no other oral applications as of yet anyways .....

[Jlane17]

Do some research before posting check out vaxart oral pill already in clinical testing with results soon to be announced. Do some homework 

[bligicka]

Vaxil and Vaxart either way Oral would be the huge advantage to getting funding and investor attention as a oral form could be sent to Africa or South America for mass distrubution without the need of syringes or fancy -80 fridges 

[Padina]

Jlane, well your position about my understanding is very wrong. USAMRIID does not have oral as part of its testing. The oral is still in early exploratory stage. USAMRIIDs job is to validate the formulation. Vaxil on the other hand will determine the best dosage form for its formulation whther oral solid dosage form or injectable. This is my field. I find it funny telling me i dont know d

[bligicka]

So where is the Oral exploratory preclinical study taking place if its not in Maryland ???                                        

[Padina]

Its anywhere but USAMRIID How do you even give tablet to mice unless of course u ground the tablet and that would have defeated the aim of the study bcos the dissolution rate will be unknown if tablet is grounded/disentegrated b4 giving the mouse? i would think tablet study should require a primate. With mice, the best form is either nasal or injection

[Red~One]

"We anticipate the first Corvax™ injections in mice will be administered during the week of December 14, 2020." News release Dec 3, 2020

[Padina]

Red-One ... Well said!!

[Padina]

Jlane17, The lethal mice being used at USAMRIID was developed in August long after the vaccine frontrunners have started their human trails so there is no way any of them could have submitted a challenge study. They only measure antibodies developed and they compared it to anbibodies from those who had survived C19 infection.. However On the therapeutic side, i am aware of companies of infected