Below an example of patience perserverance.
Hopefully Vaxil won't need 10 years, personally I'd prefer 4 or 5 months to get animal results in line with the in vivo results. Damn complex biology always getting in the way of results.
excerpt from Motley Fool article on RNA vaccine research/development
https://www.fool.com/investing/2021/04/06/pfizers-ceo-makes-a-claim-that-might-shock-anyone/
"A short history of messenger RNA
DNA stores the instructions cells use to make proteins. Messenger RNA (mRNA) is just as important: It carries the genetic code from the DNA to the protein-making machinery. Despite being relatively easy to produce, no mRNA vaccine had never won approval prior to the COVID pandemic. When research began in the 1990s, it was considered too outlandish to gain any support or funding. In fact, Katalin Kariko, the researcher who finally cracked the code, was demoted at the University of Pennsylvania for her lack of progress.
Despite her theory making biological sense, the immune system would quickly destroy any synthetic RNA it found. Ten years after her demotion, Kariko solved the mystery and published a series of papers. That research caught the eye of at least two scientists, the ones who would go on to found Moderna and BioNTech."