CEL-SCI Corporation Announces That NIAID Collaborators Have Submitted Bird Flu Study for Publication to Prestigious Scientific Journal
CEL-SCI Corporation (NYSE MKT: CVM) today announced that
its collaborators at the National Institute of Allergy and Infectious
Diseases (NIAID), part of the National Institutes of Health, USA, have
submitted for publication to a prestigious scientific journal the
results from efficacy studies in animals of L.E.A.P.S. (Ligand Epitope
Antigen Presentation System) H1N1 activated dendritic cells (DCs) to
treat the H1N1 bird flu virus. This work was conducted by scientists at
the NIAID in collaboration with scientists from CEL-SCI. The publication
addresses how the specific and selectively directed activity induced by
the LEAPS-activated DCs could be used in the possible treatment and
mitigation of pandemic flu.
This work may possibly also be applicable to the new H7N9 bird flu
strain currently detected in China since the focus of the above
publication is on a relatively highly conserved series of peptides from
the H1N1 pandemic strain. CEL-SCI’s review of information about the new
H7N9 strain suggests that the regions being used in the H1N1 treatment
submitted for publication appear to be very similar to the same regions
found in H7N9. However, not enough information is currently available
for any definite statements as to whether CEL-SCI’s potential LEAPS
treatment may be applicable to H7N9.
L.E.A.P.S. technology is a novel T-cell modulation platform technology
that enables CEL-SCI to design and synthesize non-recombinant,
proprietary immunogens. The L.E.A.P.S. technology combines a small
peptide that activates the immune system with a small peptide from a
disease-related highly conserved protein molecule.
About CEL-SCI Corporation
CEL-SCI is dedicated to research and development directed at improving
the treatment of cancer and other diseases by utilizing the immune
system, the body's natural defense system. Its lead investigational
therapy is Multikine* (Leukocyte Interleukin, Injection),
currently being studied in a pivotal global Phase III clinical trial.
CEL-SCI is also investigating an immunotherapy (LEAPS-H1N1-DC) as a
possible treatment for H1N1 hospitalized patients and as a vaccine
(CEL-2000) for Rheumatoid Arthritis (currently in preclinical testing)
using its LEAPS technology platform. The investigational immunotherapy
LEAPS-H1N1-DC treatment involves non-changing regions of H1N1 Pandemic
Flu, Avian Flu (H5N1), and the Spanish Flu, as CEL-SCI scientists are
very concerned about the possible emergence of a new more virulent
hybrid virus through the combination of H1N1 and Avian Flu, or maybe
Spanish Flu. The Company has operations in Vienna, Virginia, and in/near
Baltimore, Maryland.
For more information, please visit www.cel-sci.com.
When used in this report, the words "intends," "believes,"
"anticipated" and "expects" and similar expressions are intended to
identify forward-looking statements. Such statements are subject to
risks and uncertainties which could cause actual results to differ
materially from those projected. Factors that could cause or contribute
to such differences include, lack of regulatory clearance to proceed
with clinical trials, an inability to duplicate the clinical results
demonstrated in clinical studies that have been completed or that are
initiated in the future, timely development of any potential products
that can be shown to be safe and effective, unwillingness of regulatory
authorities to engage in further regulatory dialogue, receiving
necessary regulatory approvals, difficulties in manufacturing any of the
Company's potential products, inability to raise the necessary capital,
and the risk factors set forth from time to time in CEL-SCI
Corporation's SEC filings, including but not limited to its report on
Form 10-K for the year ended September 30, 2012. The Company undertakes
no obligation to publicly release the result of any revision to these
forward-looking statements which may be made to reflect the events or
circumstances after the date hereof or to reflect the occurrence of
unanticipated events.