NEW YORK, February 6, 2017 /PRNewswire/ --
According to Global Market Insights, Inc. the biotechnology market size was valued at over USD 330.3 billion in 2015 and will exceed USD 775.2 billion with 9.9% CAGR from
2016 to 2024. A major reason for the projected growth this sector is that chronic diseases have increased the demand for
innovations similar to DNA sequencing, microassays and recombinant DNA technologies to develop therapeutic solutions. Government
support for R&D has helped development of products and vaccines for such chronic diseases. The report indicates that the U.S.
biotechnology market size held dominant position in terms of industry revenue share followed by Europe with this trend likely to continue throughout the forecast period. Actinium Pharmaceuticals, Inc.
(NYSE: ATNM), Pulmatrix Inc. (NASDAQ: PULM), Aurinia Pharmaceuticals Inc. (NASDAQ: AUPH), Amarin Corporation (NASDAQ: AMRN),
Amicus Therapeutics Inc. (NASDAQ: FOLD)
Cancer continues to be a major area of concern. The World Health Organization indicates that the increasing use of tobacco and
alcohol consumption around the world is expected to increase the number of new cancer cases by about 70% over the next two
decades. Cancer is still one of leading causes of death worldwide and demand for cancer treatments keeps growing. The need for
improving cancer therapies is constantly pushing biotechnology companies to invest in innovation and clinical trials to find new
cancer therapeutics. According to a recent report from Mordor Intelligence, the global Cancer therapy market is estimated to grow
at 17.6% CAGR to reach $52.2 billion by 2021.
Actinium Pharmaceuticals, Inc. (NYSE: ATNM), a biopharmaceutical company developing innovative targeted therapies for
cancers lacking effective treatment options, recently announced that Dr. Mark Berger has been
appointed Chief Medical Officer effective today. Dr. Berger joins Actinium with significant drug development expertise that
includes the planning and execution of clinical trials that led to the FDA approval of Mylotarg for acute myeloid leukemia (AML)
while at Wyeth Research (now Pfizer), and Tykerb for breast cancer while at GlaxoSmithKline. He also has experience in patient
care and lab-based cancer research. Dr. Berger will report to Sandesh Seth, Actinium's Executive
Chairman.
"Dr. Berger has a stellar track record in hematology/oncology research and drug development that makes him perfectly suited
for the position of Chief Medical Officer at Actinium," said Sandesh Seth. "Dr. Berger led the
development of Mylotarg, which like Actimab-A, is a CD33 targeting agent. Mylotarg remains the only drug approved in AML in the
last several decades, and Dr. Berger was integral to Mylotarg's approval as highlighted by his presentation to ODAC. This along
with Mark's many other accomplishments in drug development, medical training and research experience gives us great confidence in
his ability to build a robust clinical development organization to execute on the clinical development of Iomab-B, Actimab-A and
our future clinical programs."
"I am impressed with the potential for Actinium's radioimmunotherapy technology," Dr. Berger said. "The data to date on
Iomab-B and Actimab-A are very compelling and suggest that radioimmunotherapy has the potential to be safe and effective
particularly in difficult clinical indications such as bone marrow transplant conditioning in patients with AML, or in the
treatment of older patients with AML. I am excited to join the Actinium team and look forward to executing on a clinical
development strategy that will bring these therapies to approval."
Clinical stage biopharmaceutical company, Pulmatrix Inc. (NASDAQ: PULM) is currently advancing a pipeline of product
candidates to treat serious chronic obstructive pulmonary diseases and asthma. The company's anti-fungal product candidate for
cystic fibrosis is the most advanced program in its pipeline of treatments for rare, orphan disease. Its PUR1500 is an iSPERSE
(inhaled small particles easily respirable and emitted) formulation that combines a kinase inhibitor with established
anti-angiogenesis activity for the treatment of idiopathic pulmonary fibrosis and its PUR0200 is also an iSPERSE formulation
that's a long-acting muscarinic antagonist bronchodilator.
Biopharmaceutical company focused on the global immunology market, Aurinia Pharmaceuticals Inc. (NASDAQ: AUPH) has
selected Worldwide Clinical Trials as its Clinical Research Organization for the AURORA Phase 3 study of volcosporin for the
treatment of active lupus nephritis. Lupus nephritis is inflammation of the kidney that is caused by systemic lupus erythematous.
"Selecting a CRO for AURORA is a key milestone for Aurinia following our successful end-of-Phase 2 meeting with the U.S. Food
& Drug Administration Division of Pulmonary, Allergy and Rheumatology Products. We are thrilled to partner with Worldwide to
support the AURORA Phase 3 clinical trial," said Charles Rowland, Chief Executive Officer of
Aurinia. "We are rapidly moving forward with our plans to bring this important therapy to market for patients living with this
devastating disease, and Worldwide's deep expertise and capabilities in managing pivotal trials will be a tremendous asset to us.
We are on track to commence the AURORA trial in the second quarter of 2017, and we expect the results from this study will
support a New Drug Application submission to the FDA."
Amarin Corporation (NASDAQ: AMRN) is a biopharmaceutical company focused on the commercialization and development of
therapeutics to improve cardiovascular health. Amarin's product development program leverages its extensive experience in lipid
science and the potential therapeutic benefits of polyunsaturated fatty acids. Vascepa® (icosapent ethyl) is Amarin's first FDA
approved product that is used together with a low-fat and low-cholesterol diet to reduce triglycerides in adults with severely
high triglycerides.
Amicus Therapeutics Inc. (NASDAQ: FOLD) is a global biotechnology company of advanced therapies that treats a range of
devastating rare and orphan diseases. The company's lead product candidate, migalastat, is a personalized medicine in late-stage
development to treat individuals with Fabry disease on the basis of their genetic diagnosis. SD-101, a product candidate in
late-stage development, is a potential first-to-market therapy for the rare genetic connective tissue disorder Epidermolysis
Bullosa. The company is leveraging its biologics and Chaperone-Advanced Replacement Therapy platform technologies to develop
novel enzyme replacement therapy products for Fabry disease, Pompe disease, and other Lysosomal Storage Disorders. Its leading
biologics program is ATB200/AT2221, a uniquely engineered Pompe disease ERT that will be administered in combination with a
pharmacological chaperone.
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