SAN DIEGO, July 12, 2017 /PRNewswire/ --
Regen BioPharma Inc. (OTCQB: RGBP) and (OTCQB: RGBPP), today reported continued progress in developing small
molecule drugs that activate and inhibit NR2F6. The Company reports that using a focused compound library and Regen's patented
screening methodology, it has identified a dynamic new chemical compound series that modulates NR2F6.
The NR2F6 nuclear receptor has been identified as a potentially very important immune cell inhibitor (an immune checkpoint)
and cancer stem cell differentiator. The NR2F6 program at Regen aims to identify antagonists of NR2F6 in an effort to unleash the
cancer-killing potential of a patient's own immune system as well as identifying agonists, which should suppress the immune
system in diseases where the immune system is over-activated, such as autoimmunity.
"We have identified a particularly active series of NR2F6 activators, which are not toxic and have an ability to activate
NR2F6 approximately 10 times more effectively than seen with our previous series," says Harry
Lander, Ph.D., MBA, President and Chief Scientific Officer of Regen. "Of particular interest is the parent structure that
this series contains. It leads us to believe that we may now understand the structural basis for activating NR2F6."
"I am very pleased that our science continues to advance positively," says David Koos, Ph.D.,
Chairman & CEO Regen BioPharma Inc. "ChemDiv's expertise in compound optimization has been a great asset as we refine our
small molecule drug development program. We continue to expect 2017 to be an extremely important year in Regen's history. Studies
were conducted for Regen by ChemDiv, Inc. (an internationally recognized contract research organization) which has been retained
by Regen."
About Regen BioPharma Inc.:
Regen BioPharma Inc. is a publicly traded biotechnology company (OTCQB: RGBP) and (OTCQB: RGBPP). The Company is focused on
the immunology and immunotherapy space. The Company is focused on rapidly advancing novel technologies through pre-clinical and
Phase I/II clinical trials. Currently, the Company is focused on small molecule therapies for treating cancer and autoimmune
disorders. Additional information on Regen BioPharma is available at http://www.regenbiopharmainc.com.
Disclaimer : This news announcement may contain forward-looking statements. Forward-looking statements are inherently
subject to risks and uncertainties, some of which cannot be predicted or quantified. Future events and actual results could
differ materially from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and
uncertainties to which forward-looking statements are subject include, but are not limited to, the effect of government
regulation, competition and other material risks.
CONTACT INFORMATION
Regen BioPharma Inc.
David R. Koos, Ph.D.
Chairman & Chief Executive Officer
Phone: +1-619-702-1404
Fax: +1-619-330-2328
david.koos@regenbiopharma.com
http://www.regenbiopharma.com
SOURCE Regen BioPharma, Inc.