NEW YORK, May 31, 2018 /PRNewswire/ --
According to a publication by Research and Markets, the global stem cells market was valued at US$ 5.2
billion in 2016 and is expected to reach US$ 13.7 billion by 2025 expanding at a CAGR of
10.50% from 2017 to 2025. Stem cells therapy is anticipated to transform medical treatments in the coming decades. The report
indicates that Drug discovery and development segment will be the fastest growing market throughout the forecast period
2017-2025, due to the factors such as increasing demand for stem cell technology from pharmaceutical giants to reduce the high
attrition rate of late stage drug candidates and build innovative cellular models. International Stem Cell Corporation (OTC:
ISCO), Cytori Therapeutics, Inc. (NASDAQ: CYTX), Vericel Corporation (NASDAQ: VCEL), Vital Therapies, Inc. (NASDAQ: VTL),
Pluristem Therapeutics Inc. (NASDAQ: PSTI)
An example of a recent advancement made using stem cells was reported earlier in 2017. According to Reuters, Scientists have
successfully used "reprogrammed" stem cells to restore functioning brain cells in monkeys, raising hopes of helping patients with
Parkinson's disease in the future. "This is extremely promising research demonstrating that a safe and highly effective cell
therapy for Parkinson's can be produced in the lab," said Tilo Kunath of the MRC Centre for
Regenerative Medicine, University of Edinburgh, who was not involved in the research.
International Stem Cell Corp. (OTCQB: ISCO) announced yesterday that, "a paper prepared by the Company has been
published in Volume 12, Issue 5 of the Journal of Tissue Engineering and Regenerative Medicine, a prestigious peer-reviewed
scientific journal. Due to its scientific relevance, the article has been featured on the cover of the journal's May 2018 issue.
The article, entitled "Supplementation of Specific Carbohydrates Results in Enhanced Deposition of Chondrogenic-Specific
Matrix during Mesenchymal Stem Cell Differentiation," discusses a new scalable system developed by ISCO that permits the
generation of functional human cartilage tissue derived from the patient's own skin or fat tissue. This process has the capacity
to provide greater stability than other tissue that is currently available for the treatment of osteoarthritis, the most common
chronic joint condition.
Using this new system, ISCO scientists generated a healthy cartilage‐specific matrix from human mesenchymal stem cells that
had significantly higher viability and cartilage specific properties, including: proteoglycan, aggrecan, hyaluronic acid, and
collagen II deposition and glycosaminoglycan production. This new cartilage-specific matrix was built in 3D format and is ready
for further therapeutic development.
"While the treatment of Parkinson's disease has always been at the forefront of our research efforts, we are also pursuing
various other therapeutic indications. In one of those other areas,our R&D Team has significantly improved the process by
which we can use the patient's own mesenchymal stem cells to potentially treat osteoarthritis," commented Russell Kern, PhD, ISCO's Executive Vice President and Chief Scientific Officer. "We are also thrilled to
announce that this research gives us a basis to launch program to develop supplements designed to potentially reduce joint pain
and improve overall mobility," he continued.
According to the Centers for Disease Control and Prevention (CDC), osteoarthritis is the most common form of degenerative
joint disease and affects as many as 27 million Americans.
Characterized by progressive erosion of the articular cartilage, osteoarthritis can damage any joint in the body-most commonly
in the hands, knees, hips, and spine. The erosion of articular cartilage leads to joint pain, stiffness, and impaired
mobility.
Healthy cartilage permits bones to glide over one another. It also absorbs energy from the initial burst of physical movement.
In osteoarthritis, the surface layer of cartilage collapses and wears away. This allows bones under the cartilage to rub against
one another, causing pain, swelling, and loss of motion of the joint."
Cytori Therapeutics, Inc. (NASDAQ: CYTX) is a therapeutics company developing regenerative and oncologic therapies from
its proprietary cell therapy and nanoparticle platforms for a variety of medical conditions. Data from preclinical studies and
clinical trials suggest that Cytori Cell Therapy™ acts principally by improving blood flow, modulating the immune system, and
facilitating wound repair. On March 28, 2018, the company announced that full enrollment has been
reached in the ADRESU investigator-initiated clinical trial of Cytori Cell Therapy™ for men with stress urinary incontinence as a
complication of prostate intervention. A total of 45 patients, all treated in Japan, were
enrolled in this potential approval trial. ADRESU is an investigator-initiated, multicenter, 45 patient, open-label, single arm
clinical trial of Cytori's ECCI-50 cellular therapeutic, comprised of Celution®-prepared autologous Adipose Derived Regenerative
Cells (ADRCs) and Adipose Cells.
Vericel Corporation (NASDAQ: VCEL) is a leader in advanced cell therapies for the sports medicine and severe burn care
markets. The company markets two cell therapy products in the United States. Earlier this month,
the company reported financial results and business highlights for the first quarter ended March 31,
2018. Total net revenues of $18.0 million compared to $9.4
million in the first quarter of 2017; first quarter 2017 revenues included a $2.8 million
revenue reserve for Carticel® and MACI® related to a contractual dispute between one of the Company's pharmacy providers and a
third-party payer. The company achieved record first quarter revenues and the fourth straight quarter of 30% or greater revenue
growth versus the same quarter of the prior year.
Vital Therapies, Inc. (NASDAQ: VTL) is a biotherapeutic company developing a cell-based therapy targeting the treatment
of acute forms of liver failure. The Company's ELAD System is an extracorporeal human allogeneic cellular liver therapy currently
in phase 3 clinical trials. On March 22, 2018, the company announced that the VTL-308 phase 3 trial
has reached its enrollment target of 150 subjects. VTL-308 is the Company's phase 3 randomized, controlled, open-label trial,
designed to evaluate the ELAD System in subjects with severe alcoholic hepatitis (sAH). The trial, which enrolled its first
subject in May of 2016, was designed based on learnings from pre-specified and post-hoc analyses of the Company's VTI-208
clinical trial. Subjects in VTL-308 were randomized 1:1 to either ELAD plus standard-of-care, or standard-of-care alone. The
primary endpoint is overall survival through at least 91 days assessed using the Kaplan Meier statistical method.
Pluristem Therapeutics Inc. (NASDAQ: PSTI) is a leading developer of placenta-based cell therapy products. The Company
has reported robust clinical trial data in multiple indications for its patented PLX cells and is entering latestage trials in
several indications. On April 30, 2018, the company announced that the U.S. Food and Drug
Administration (FDA) has cleared the Company's Investigational New Drug (IND) application for its PLX-R18 cell therapy in the
treatment of acute radiation syndrome (ARS). The U.S. National Institutes of Health's National Institute of Allergy and
Infectious Diseases (NIAID) sponsored and completed a successful Phase II-equivalent study of PLX-R18 in the treatment of ARS via
the FDA's animal rule pathway. PLX-R18 is Pluristem's second cell therapy product in development. It is designed to treat bone
marrow that is unable to produce enough blood cells due to a variety of causes including ARS, certain cancers or cancer
treatments, or immune-mediated bone marrow failure.
Subscribe Now! Watch us report LIVE https://www.youtube.com/FinancialBuzzMedia
Follow us on Twitter for real time Financial News Updates: https://twitter.com/financialbuzz
Follow and talk to us on Instagram: https://www.instagram.com/financialbuzz
Facebook Like Us to receive live feeds: https://www.facebook.com/Financialbuzz/
About FinancialBuzz.com
FinancialBuzz.com, a leading financial news informational web portal designed to provide the latest trends in Market News,
Investing News, Personal Finance, Politics, Entertainment, in-depth broadcasts on Stock News, Market Analysis and Company
Interviews. A pioneer in the financially driven digital space, video production and integration of social media,
FinancialBuzz.com creates 100% unique original content. FinancialBuzz.com also provides financial news PR dissemination,
branding, marketing and advertising for third parties for corporate news and original content through our unique media platform
that includes Newswire Delivery, Digital Advertising, Social Media Relations, Video Production, Broadcasting, and Financial
Publications.
Please Note: FinancialBuzz.com is not a financial advisory or advisor, investment advisor or broker-dealer and do not
undertake any activities that would require such registration. The information provided on http://www.FinancialBuzz.com (the 'Site') is either original financial news or paid advertisements provided
[exclusively] by our affiliates (sponsored content), FinancialBuzz.com, a financial news media and marketing firm enters into
media buys or service agreements with the companies which are the subject to the articles posted on the Site or other editorials
for advertising such companies. We are not an independent news media provider and therefore do not represent or warrant that the
information posted on the Site is accurate, unbiased or complete. FinancialBuzz.com receives fees for producing and presenting
high quality and sophisticated content on FinancialBuzz.com along with other financial news PR media services. FinancialBuzz.com
does not offer any personal opinions, recommendations or bias commentary as we purely incorporate public market information along
with financial and corporate news. FinancialBuzz.com only aggregates or regurgitates financial or corporate news through our
unique financial newswire and media platform. For International Stem Cell Corp., financial news dissemination and PR services,
FinancialBuzz.com has been compensated four thousand dollars by meridian ventures. Our fees may be
either a flat cash sum or negotiated number of securities of the companies featured on this editorial or site, or a combination
thereof. The securities are commonly paid in segments, of which a portion is received upon engagement and the balance is paid on
or near the conclusion of the engagement. FinancialBuzz.com will always disclose any compensation in securities or cash payments
for financial news PR advertising. FinancialBuzz.com does not undertake to update any of the information on the editorial or Site
or continue to post information about any companies the information contained herein is not intended to be used as the basis for
investment decisions and should not be considered as investment advice or a recommendation. The information contained herein is
not an offer or solicitation to buy, hold or sell any security. FinancialBuzz.com, members and affiliates are not responsible for
any gains or losses that result from the opinions expressed on this editorial or Site, company profiles, quotations or in other
materials or presentations that it publishes electronically or in print. Investors accept full responsibility for any and all of
their investment decisions based on their own independent research and evaluation of their own investment goals, risk tolerance,
and financial condition. FinancialBuzz.com. By accessing this editorial and website and any pages thereof, you agree to be bound
by the Terms of Use and Privacy Policy, as may be amended from time to time. None of the content issued by FinancialBuzz.com
constitutes a recommendation for any investor to purchase, hold or sell any particular security, pursue a particular investment
strategy or that any security is suitable for any investor. This publication is provided by FinancialBuzz.com. Each investor is
solely responsible for determining whether a particular security or investment strategy is suitable based on their objectives,
other securities holdings, financial situation needs, and tax status. You agree to consult with your investment advisor, tax and
legal consultant before making any investment decisions. We make no representations as to the completeness, accuracy or timeless
of the material provided. All materials are subject to change without notice. Information is obtained from sources believed to be
reliable, but its accuracy and completeness are not guaranteed. For our full disclaimer, disclosure and Terms of Use, please
visit: http://www.financialbuzz.com.
Media Contact:
info@financialbuzz.com
+1-877-601-1879
URL: http://www.FinancialBuzz.com
SOURCE FinancialBuzz.com