BUFFALO, N.Y., June 04, 2018 (GLOBE NEWSWIRE) -- Athenex, Inc. (Nasdaq:ATNX), a global biopharmaceutical company dedicated to
the discovery, development and commercialization of novel therapies for the treatment of cancer and related conditions, today
announced that two posters on Oraxol will be presented at the American Society of Clinical Oncology (ASCO) Meeting, taking place
June 1-5, 2018 in Chicago, IL.
Abstract Title: A phase I study to evaluate safety, tolerability, pharmacokinetics and activity of oraxol in
patients (pts) with advanced malignancies.
Abstract ID: 2526
Dr Ma, Wan Wee (Mayo Clinic, Rochester, USA)
Poster Session: Clinical Pharmacology and Experimental Therapeutics
Date: 06/04/2018, 8:00 AM - 11:30 AM
Abstract Title: An open-label, randomized cross-over bioavailability and extension study of oral paclitaxel and
HM30181 compared with weekly intravenous (IV) paclitaxel in patients with advanced solid tumours.
Abstract ID: 2569
Dr Jackson, Christopher (Otago University, Dunedin, NZ)
Poster Session: Clinical Pharmacology and Experimental Therapeutics
Date: 06/04/2018, 8:00 AM - 11:30 AM
About Athenex, Inc.
Founded in 2003, Athenex, Inc. is a global clinical stage biopharmaceutical company dedicated to becoming a leader in the
discovery and development of next generation drugs for the treatment of cancer. Athenex is organized around three
platforms, including an Oncology Innovation Platform, a Commercial Platform and a Global Supply Chain Platform. Athenex’s Oncology
Innovation Platform generates clinical candidates through an extensive understanding of kinases, including novel binding sites and
human absorption biology, as well as through the application of Athenex’s proprietary research and selection processes in the lab.
The Company’s current clinical pipeline is derived from two different platform technologies Athenex calls Orascovery and
Src Kinase Inhibition. The Orascovery platform is based on the novel oral P-glycoprotein pump inhibitor molecule HM30181A, through
which Athenex is able to facilitate oral absorption of traditional cytotoxics, which Athenex believes may offer
improved patient tolerability and efficacy as compared to IV administration of the same cytotoxics. The Orascovery platform was
developed by Hanmi Pharmaceuticals and licensed exclusively to Athenex for all major worldwide territories
except Korea, which is retained by Hanmi. The Src Kinase Inhibition platform refers to novel small molecule compounds that
have multiple mechanisms of action, including the inhibition of the activity of Src Kinase and the inhibition of tubulin
polymerization during cell division. Athenex believes the combination of these mechanisms of action provides a broader
range of anti-cancer activity as compared to either mechanism of action alone. Athenex’s employees worldwide are dedicated to
improving the lives of cancer patients by creating more active and tolerable treatments. Athenex has offices
in Buffalo and Clarence, New York; Cranford, New Jersey; Houston, Texas; Chicago, Illinois; Hong
Kong; Taipei, Taiwan and multiple locations in Chongqing, China.
CONTACT:
Jim Polson
Tel: +1-716-427-2952
Athenex, Inc.
