Lausanne, Switzerland, July 24, 2018 - AC Immune SA (NASDAQ: ACIU), a Swiss-based, clinical-stage
biopharmaceutical company focused on neurodegenerative diseases, today announced the closing of its previously announced first
subscription rights offering and underwritten primary offering of common shares, including the exercise in full by the underwriters
of their option to purchase an additional 1,108,695 additional shares at the price per common share of USD 11.75. The exercise of
the option to purchase additional shares brought the total number of common shares sold by AC Immune to 8,500,000 shares and
increased the amount of gross proceeds raised in the offerings, before underwriting discounts and estimated expenses of the
offering, to approximately USD 99.9 million.
Jefferies LLC, Leerink Partners LLC and UBS Investment Bank acted as joint book-running managers for the first
subscription rights offering and the primary offering. H.C. Wainwright & Co. acted as lead manager for these offerings.
The shares were offered by AC Immune pursuant to a registration statement that was previously filed with the
Securities and Exchange Commission ("SEC"). A prospectus supplement relating to, and describing the terms of, the offering has been
filed with the SEC and is available on the SEC's web site at www.sec.gov. Copies of the final prospectus supplement for these
offerings may be obtained from: Jefferies, LLC Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor,
New York, NY 10022, by emailing Prospectus_Department@Jefferies.com; Leerink Partners LLC, Attention: Syndicate Department, One
Federal Street, 37th Floor, Boston, MA 02110 or by email at syndicate@leerink.com, or by calling (800) 808-7525 ex. 6132; or from UBS Investment Bank,
Attention Prospectus Department, 1285 Avenue of the Americas, New York, NY 10019 or by email at ol-prospectusrequest@ubs.com, or by calling (888) 827-7275.
A second subscription rights offering to eligible shareholders to subscribe for up to 1.5 million newly
issued common shares on a pro rata basis began at 3:00 a.m. (New York City time) on July 20, 2018, and will expire at 4:00 p.m.
(New York City time) on July 27, 2018. Preemptive subscription rights not validly exercised within the applicable subscription
period will lapse and become null and void without compensation, and the new common shares for which preemptive subscription rights
have not been validly exercised will be available for allocation by the Company.
Any eligible shareholder interested in participating in the second subscription rights offering should contact
Georgeson LLC, acting as information agent, by calling (888) 613-9817 or +1 781-575-2137 prior to the expiration of the
subscription period for the second subscription rights offering. For this offering, eligible shareholders will be sent additional
documentation through Computershare or the banking system.
The second subscription rights offering will be made pursuant to an effective shelf registration statement of
the Company previously filed with the U.S. Securities and Exchange Commission. This offering may be made only by means of a
prospectus supplement and the accompanying prospectus. Copies of the preliminary prospectus for this offering, when available, may
be obtained from the Company in writing at AC Immune SA, EPFL Innovation Park Building B, 1015 Lausanne, Switzerland or via
telephone by calling +41 21 345 91 21.
Each exercise of preemptive subscription rights in the second subscription rights offering, is subject to market
and other conditions and the restrictions set forth in the Company's articles of association and may be subject to certain
restrictions under applicable laws and regulations.
Disclaimer
This press release shall not constitute an offer to sell or the solicitation of an offer to buy any securities, nor shall there be
any sale of any securities, in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to
registration or qualification under the securities laws of any such state or jurisdiction. This press release is not a prospectus
within the meaning of article 652a of the Swiss Code of Obligations, nor is it a listing prospectus of any exchange or regulated
trading facility in Switzerland. Copies of this press release may not be sent to jurisdictions, or distributed in or sent from
jurisdictions, in which this is barred or prohibited by law.
About AC Immune
AC Immune is a clinical-stage Swiss-based biopharmaceutical company, listed on Nasdaq, which aims to become a global leader in
precision medicine for neurodegenerative diseases. The Company designs, discovers and develops therapeutic as well as diagnostic
products intended to prevent and modify diseases caused by misfolding proteins.
For further information, please contact: