STAMFORD, Conn., July 23, 2018 (GLOBE NEWSWIRE) -- Cara Therapeutics, Inc. (Nasdaq:CARA), a clinical-stage
biopharmaceutical company focused on developing and commercializing new chemical entities designed to alleviate pruritus and pain
by selectively targeting kappa opioid receptors, today announced the closing of its underwritten public offering of 5,175,000
shares of its common stock at a public offering price of $19.00 per share, including 675,000 shares sold pursuant to the
underwriters’ full exercise of their option to purchase additional shares. All of the shares in the offering were sold by Cara
Therapeutics. The gross proceeds from the offering, before deducting underwriting discounts and commissions and estimated offering
expenses payable by Cara Therapeutics, were $98.3 million. Cara Therapeutics intends to use the net proceeds from the
offering to fund CR845/difelikefalin’s clinical and research development activities, as well as for working capital and other
general corporate purposes.
Jefferies and BofA Merrill Lynch acted as lead joint book-running managers for the offering. Piper Jaffray & Co.
and Stifel also acted as book-runners for the offering. Canaccord Genuity, Needham & Company, H.C. Wainwright & Co. and Janney
Montgomery Scott acted as co-managers for the offering.
The offering was made only by means of a written prospectus supplement and prospectus forming part of a shelf
registration statement previously filed with and declared effective by the Securities and Exchange Commission (SEC). Copies of the
final prospectus supplement and accompanying prospectus may be obtained by contacting Jefferies LLC, Attention: Equity
Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor, New York, NY 10022, by telephone at (877) 821-7388, or by email at
prospectus_department@jefferies.com; BofA Merrill Lynch, NC1-004-03-43, 200 North College Street, 3rd Floor, Charlotte, NC
28255-0001, Attention: Prospectus Department, or by email at dg.prospectus_requests@baml.com; Piper Jaffray & Co., Attention:
Prospectus Department, 800 Nicollet Mall, J12S03, Minneapolis, MN 55402, or by telephone at (800) 747-3924, or by email at
prospectus@pjc.com, or from Stifel, Nicolaus & Company, Incorporated, Attention: Syndicate, One Montgomery Street, Suite 3700, San
Francisco, CA 94104, or by telephone at (415) 364-2720, or by email at syndprospectus@stifel.com.
This press release shall not constitute an offer to sell or a solicitation of an offer to buy these securities,
nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be
unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.
About Cara Therapeutics
Cara Therapeutics is a clinical-stage biopharmaceutical company focused on developing and commercializing new
chemical entities designed to alleviate pruritus and pain by selectively targeting peripheral kappa opioid receptors (KORs). Cara
is developing a novel and proprietary class of product candidates, led by KORSUVA™ (CR845/difelikefalin), a first-in-class KOR
agonist that targets the body's peripheral nervous system, as well as certain immune cells. In Phase 2 trials, KORSUVA injection
has demonstrated statistically significant reductions in itch intensity and concomitant improvement in quality of life measures in
hemodialysis patients with moderate-to-severe chronic kidney disease-associated pruritus (CKD-aP), and is currently being
investigated in Phase 3 trials in hemodialysis patients with CKD-aP. Additionally, in a recently completed Phase 2/3 trial in
post-operative patients, I.V. CR845/difelikefalin has demonstrated reduction in moderate-to-severe pain, while also reducing the
incidence and intensity of nausea and vomiting throughout the post-operative period.
Forward-Looking Statements
This press release contains or may imply “forward-looking statements” within the meaning of Section 27A of the
Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Because such statements
deal with future events and are based on Cara Therapeutics’ current expectations, they are subject to various risks and
uncertainties and actual results, performance or achievements of Cara Therapeutics could differ materially from those described in
or implied by the statements in this press release. For example, forward-looking statements include statements regarding the use of
proceeds of Cara Therapeutics’ public offering. These forward-looking statements are subject to other risks and uncertainties
discussed in Cara Therapeutics’ filings with the SEC; including in the “Risk Factors” section of Cara Therapeutics’ Annual Report
on Form 10-K for the year ended December 31, 2017, filed with the SEC on March 15, 2018 and subsequent filings with the SEC. Except
as otherwise required by law, Cara Therapeutics disclaims any intention or obligation to update or revise any forward-looking
statements, which speak only as of the date hereof, whether as a result of new information, future events or circumstances or
otherwise.
CORPORATE CONTACT:
Derek Chalmers, Ph.D., D.Sc.
President & CEO
Cara Therapeutics, Inc.
203-406-3700
MEDIA CONTACT:
Annie Starr
6 Degrees
973-415-8838
astarr@6degreespr.com
INVESTOR CONTACT:
Michael Schaffzin
Stern Investor Relations, Inc.
212-362-1200
michael@sternir.com
