CAMBRIDGE, Mass., July 31, 2018 (GLOBE NEWSWIRE) -- Aileron Therapeutics (Nasdaq:ALRN), the leader in the field of
stapled peptide therapeutics for cancers and other diseases, today announced that the Company will report its second quarter 2018
financial results on Tuesday, August 7, 2018 after the close of market.
About Aileron
Aileron is a clinical-stage biopharmaceutical company advancing stapled peptides, a novel class of therapeutics for cancers and
other diseases. Stapled peptides are chemically stabilized alpha-helical peptides that are modified to improve their stability and
cell penetrability while maintaining high affinity for large protein surfaces. Our goal is to use our proprietary stapled peptide
drug platform to create first-in-class therapeutics, like ALRN-6924, that may be able to address historically undruggable targets
and complex mechanisms that underlie many diseases with high unmet medical need. Our platform enables us to chemically stabilize
and improve the performance and activity of a broad range of alpha-helical peptides that we believe can potentially activate and
inhibit key cellular functions that are otherwise difficult to target with existing drug technologies, including small molecules
and monoclonal antibodies. For more information, visit www.aileronrx.com.
About ALRN-6924
ALRN-6924 is a first-in-class product candidate designed to reactivate wild type p53 tumor suppression by disrupting the
interactions between p53 and the two primary p53 suppressor proteins, MDMX and MDM2. Aileron believes ALRN-6924 is the first and
only product candidate in clinical development that can equipotently bind to and disrupt the interaction of MDMX and MDM2 with p53.
Based on preclinical data and preliminary evidence of safety and anti-tumor activity in its ongoing clinical trials, there may be a
significant opportunity to develop ALRN-6924 as a monotherapy or combination therapy for a wide variety of solid and liquid tumors.
ALRN-6924 is currently being evaluated in multiple clinical trials for the treatment of acute myeloid leukemia (AML), advanced
myelodysplastic syndrome (MDS) and peripheral T-cell lymphoma (PTCL). For information about its clinical trials, please
visit www.clinicaltrials.gov.
Source: Aileron Therapeutics
Investor: Don Dougherty, CFO 617-995-0900 ddougherty@aileron.com
