HOUSTON and VANCOUVER, Aug. 29,
2018 /CNW/ - ESSA Pharma Inc. (TSX-V: EPIX, NASDAQ: EPIX) ("ESSA" or the "Company"), a pharmaceutical company focused
on developing novel therapies for the treatment of prostate cancer, today announced that David R.
Parkinson, President and Chief Executive Officer, will be presenting at the 20th Annual Rodman & Renshaw
Global Investment Conference, sponsored by H.C. Wainwright, in New York City on Wednesday, September 5th, at 5:05 PM Eastern Standard Time at the St.
Regis Hotel in New York.
Dr. Parkinson will provide a corporate overview of the Company's business and will be available for one-on-one meetings from
September 4 - 6, 2018. ESSA's Chief Financial Officer, David S.
Wood, and Chief Operating Officer, Peter Virsik, will also be in attendance.
The presentation will be webcast live. To access the webcast, please visit http://wsw.com/webcast/rrshq28/epi/. The webcast replay will
remain available on the Company's website (www.essapharma.com) for 90 days following the live presentation.
Presentation Details :
Event:
|
20th Annual Rodman & Renshaw Global Investment Conference,
sponsored by H.C. Wainwright
|
Presentation Date:
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Wednesday, September 5, 2018
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Presentation Time:
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5:05 PM Eastern Standard Time
|
Location:
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Fontainebleau Room (2nd floor), St. Regis Hotel, New York, New
York
|
URL:
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http://wsw.com/webcast/rrshq28/epi/
|
About ESSA Pharma Inc.
ESSA is a pharmaceutical company focused on developing novel and proprietary therapies for the treatment of
castration-resistant prostate cancer ("CRPC") in patients whose disease is progressing despite treatment with current therapies.
ESSA believes that its proprietary compounds can significantly expand the interval of time in which patients suffering from CRPC
can benefit from hormone-based therapies, by disrupting the androgen receptor ("AR") signaling pathway that drives prostate
cancer growth and by preventing AR transcriptional activity by binding selectively to the N-terminal domain ("NTD") of the AR. A
functional NTD is essential for transactivation of the AR. In preclinical studies, blocking the NTD has demonstrated the
capability to overcome the known AR-dependent mechanisms of CRPC. ESSA was founded in 2009.
About Prostate Cancer
Prostate cancer is the second-most commonly diagnosed cancer among men and the fifth most common cause of male cancer
death worldwide (Globocan, 2012). Adenocarcinoma of the prostate is dependent on androgen for tumor progression and depleting or
blocking androgen action has been a mainstay of hormonal treatment for over six decades. Although tumors are often initially
sensitive to medical or surgical therapies that decrease levels of testosterone, disease progression despite castrate levels of
testosterone generally represents a transition to the lethal variant of the disease, metastatic CPRC ("mCRPC"), and most patients
ultimately succumb to the illness. The treatment of mCRPC patients has evolved rapidly over the past five years. Despite these
advances, additional treatment options are needed to improve clinical outcomes in patients, particularly those who fail existing
treatments including abiraterone or enzalutamide, or those who have contraindications to receive those drugs. Over time, patients
with mCRPC generally experience continued disease progression, worsening pain, leading to substantial morbidity and limited
survival rates. In both in vitro and in vivo animal studies, ESSA's novel approach to blocking the androgen pathway has been
shown to be effective in blocking tumor growth when current therapies are no longer effective.
Forward-Looking Statement
Disclaimer
This release contains certain information which, as presented, constitutes "forward-looking information" within the meaning of
the Private Securities Litigation Reform Act of 1995 and/or applicable Canadian securities laws. Forward-looking information
involves statements that relate to future events and often addresses expected future business and financial performance,
containing words such as "anticipate", "believe", "plan", "estimate", "expect", and "intend", "potential", "promising",
"refocus", statements that an action or event "may", "might", "could", "should", or "will" be taken or occur, or other similar
expressions and includes, but is not limited to, statements regarding the acceleration of ESSA's next-generation NTD-inhibitor
aniten compounds and timing of nomination of the next-generation compound and the anticipated timing of the IND filing for the
aniten program.
Forward-looking statements and information are subject to various known and unknown risks and uncertainties, many of which
are beyond the ability of ESSA to control or predict, and which may cause ESSA's actual results, performance or achievements to
be materially different from those expressed or implied thereby. Such statements reflect ESSA's current views with respect to
future events, are subject to risks and uncertainties and are necessarily based upon a number of estimates and assumptions that,
while considered reasonable by ESSA as of the date of such statements, are inherently subject to significant medical, scientific,
business, economic, competitive, political and social uncertainties and contingencies. In making forward-looking statements, ESSA
may make various material assumptions, including but not limited to (i) the accuracy of ESSA's financial projections; (ii)
obtaining positive results of clinical trials; (iii) obtaining necessary regulatory approvals; and (iv) general business, market
and economic conditions.
Forward-looking information is developed based on assumptions about such risks, uncertainties and other factors set out
herein and in ESSA's Annual Report on Form 20-F for the year ended September 30, 2017 under the
heading "Risk Factors", a copy of which is available on ESSA's profile on the SEDAR website at www.sedar.com, ESSA's profile
on EDGAR at www.sec.gov, and as otherwise disclosed from time to time on ESSA's SEDAR profile. Forward-looking
statements are made based on management's beliefs, estimates and opinions on the date that statements are made and ESSA
undertakes no obligation to update forward-looking statements if these beliefs, estimates and opinions or other circumstances
should change, except as may be required by applicable Canadian and United States securities
laws. Readers are cautioned against attributing undue certainty to forward-looking statements.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture
Exchange) accepts responsibility for the adequacy or accuracy of this release.
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SOURCE ESSA Pharma Inc
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