CALGARY, Alberta and SAN DIEGO, Sept. 06, 2018 (GLOBE NEWSWIRE) -- Oncolytics Biotech® Inc. (NASDAQ:
ONCY) (TSX: ONC), currently developing REOLYSIN® (pelareorep), an intravenously delivered immuno-oncolytic virus turning
cold tumors hot, today announced that it has entered into a Master Clinical Supply Agreement (Agreement) with F. Hoffmann-La Roche
Ltd (Roche) to supply atezolizumab (Tecentriq®) for use in the company’s clinical development program.
“The supply agreement enables us to further investigate pelareorep’s impact on cancer treatments in combination
with atezolizumab,” said Dr. Matt Coffey President and CEO of Oncolytics Biotech. “We plan on incorporating this anti-PD-L1
cancer immunotherapy into our clinical program immediately. Data from these studies will broaden our experience with this drug
class as we look to demonstrate the impact of pelareorep with checkpoint inhibitors.”
Under this five-year Master Clinical Supply Agreement, Roche will supply atezolizumab for the proposed clinical
trial with both parties having access to the clinical data.
About Pelareorep
Pelareorep, is a non-pathogenic, proprietary isolate of the unmodified reovirus: a first-in-class intravenously delivered
immuno-oncolytic virus being evaluated for the treatment of solid tumors and hematological malignancies. The compound induces
selective tumor lysis and promotes an inflamed tumor phenotype through innate and adaptive immune responses to treat a variety of
cancers.
About Oncolytics Biotech Inc.
Oncolytics is a biotechnology company developing pelareorep, an intravenously delivered immuno-oncolytic virus. The compound
induces selective tumor lysis and promotes an inflamed tumor phenotype -- turning "cold" tumors "hot" -- through innate and
adaptive immune responses to treat a variety of cancers. Oncolytics' clinical development program emphasizes three pillars:
chemotherapy combinations to trigger selective tumor lysis and immuno-therapy and immune modulator (IMiD) combinations to produce
innate and adaptive immune responses. Oncolytics is currently conducting and planning additional studies in combination with
checkpoint inhibitors and targeted and IMiD therapies in solid and hematological malignancies, as it prepares for a phase 3
registration study in metastatic breast cancer. For further information, please visit: www.oncolyticsbiotech.com.
Tecentriq® (atezolizumab) is a registered trademark of Genentech, a member of the Roche Group.
This press release contains forward-looking statements, within the meaning of Section 21E of the Securities
Exchange Act of 1934, as amended and forward-looking information under applicable Canadian securities laws (such forward-looking
statements and forward-looking information are collectively referred to herein as “forward-looking statements”). Forward-looking
statements, including the Company's belief as to the potential and mode of action of REOLYSIN, also known as pelareorep, as a
cancer therapeutic; and other statements related to anticipated developments in the Company's business and technologies involve
known and unknown risks and uncertainties, which could cause the Company's actual results to differ materially from those in the
forward-looking statements. Such risks and uncertainties include, among others, the availability of funds and resources to pursue
research and development projects, the efficacy of pelareorep as a cancer treatment, the success and timely completion of clinical
studies and trials, the Company's ability to successfully commercialize pelareorep, uncertainties related to the research and
development of pharmaceuticals, uncertainties related to the regulatory process and general changes to the economic environment.
Investors should consult the Company's quarterly and annual filings with the Canadian and U.S. securities commissions for
additional information on risks and uncertainties relating to the forward-looking statements. Investors are cautioned against
placing undue reliance on forward-looking statements. The Company does not undertake to update these forward-looking statements,
except as required by applicable laws.
