GARDEN CITY, N.Y. and REHOVOT, Israel, Oct. 16, 2018 (GLOBE NEWSWIRE) -- AIT Therapeutics, Inc. (OTCQB: AITB), a
clinical-stage medical device and biopharmaceutical company focused on developing inhaled Nitric Oxide (NO) for the treatment of
patients with respiratory conditions including serious lung infections and pulmonary hypertension, today announced a poster
presentation on inhaled NO at the North American Cystic Fibrosis Conference, being held October 18-20 in Denver, CO.
The poster will contain results of high-dose nitric oxide as an antibacterial agent in the treatment of
Mycobacterium abscessus complex (MABSC). MABSC is one of the most antibiotic-resistant pathogens and difficult to
treat species of nontuberculous mycobacteria (NTM). There are currently no approved treatments for MABSC.
“We are pleased to present these data demonstrating the antibacterial activity of high-dose NO suggesting its
potential as a therapy for MABSC,” said Steven Lisi, Chairman and Chief Executive Officer of AIT Therapeutics. “We look forward to
our continued development of NO as a therapy in this difficult-to-treat disease.”
Details of the poster presentation is as follows:
| Title: |
High-Dose Inhaled Nitric Oxide as a Potential Therapy Against Mycobacterium
Abscessus Lung Infection in Cystic Fibrosis |
| Author: |
Kristijan Bogdanovski |
| Date/Time: |
Thursday, October 18 / 11:15am - 1:45pm CT |
About Nitric Oxide (NO)
Nitric Oxide (NO) is a powerful molecule proven to play a critical role in a broad array of biological
functions. In the airways, NO is believed to play a key role in the innate immune system at concentrations of approximately
200 ppm. In vitro studies suggest that NO possesses anti-microbial activity not only against common bacteria, both
gram-positive and gram-negative, but also against other diverse organisms including mycobacteria, fungi, yeast and parasites, and
has the potential to eliminate multi-drug resistant strains.
About Mycobacterium abscessus complex (MABSC) of the Lungs
MABSC is the most aggressive and difficult to treat species of nontuberculous mycobacteria (NTM). There are currently no approved
treatments for MABSC. Current standard-of-care is a cocktail of antibiotics that often proves to be ineffective with severe adverse
effects. Most patients suffering from MABSC have an underlying disease, such as cystic fibrosis or chronic obstructive
pulmonary disease (COPD). The median survival of those suffering from MABSC is less than 5 years.
About AIT Therapeutics Inc.
AIT Therapeutics Inc. is a clinical-stage medical device and biopharmaceutical company using nitric oxide (NO) to treat respiratory
and other diseases. The Company is currently applying its therapeutic expertise to treat lower respiratory tract infections that
are not effectively addressed with current standards of care, as well as pulmonary hypertension, in various settings. AIT is
currently advancing its revolutionary NO Generator and Delivery System in clinical trials for the treatment of bronchiolitis and
severe lung infections such as nontuberculous mycobacteria (NTM). For more information, visit www.AIT-Pharm.com.
Forward-Looking Statement
This press release contains “forward-looking statements.” Forward-looking statements include statements about our
expectations, beliefs, or intentions regarding our product offerings, business, financial condition, results of operations,
strategies or prospects. You can identify such forward-looking statements by the words “expects,” “intends,” “plans,” “projects,”
“believes,” “estimates,” “likely,” “goal,” “assumes,” “targets” and similar expressions and/or the use of future tense or
conditional constructions (such as “will,” “may,” “could,” “should” and the like) and by the fact that these statements do not
relate strictly to historical or current matters. Rather, forward-looking statements relate to anticipated or expected events,
activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet
occurred, these statements are inherently subject to risks and uncertainties that could cause our actual results to differ
materially from any future results expressed or implied by the forward-looking statements. These forward-looking statements are
only predictions and reflect our views as of the date they are made with respect to future events and financial performance. Many
factors could cause our actual activities or results to differ materially from the activities and results anticipated in
forward-looking statements, including risks related to: our approach to discover and develop novel drugs, which is unproven and may
never lead to marketable products; our ability to fund and the results of further pre-clinical and clinical trials; obtaining,
maintaining and protecting intellectual property utilized by our products; our ability to enforce our patents against infringers
and to defend our patent portfolio against challenges from third parties; our ability to obtain additional funding to support our
business activities; our dependence on third parties for development, manufacture, marketing, sales, and distribution of products;
the successful development of our product candidates, all of which are in early stages of development; obtaining regulatory
approval for products; competition from others using technology similar to ours and others developing products for similar uses;
our dependence on collaborators; and our short operating history. We undertake no obligation to update, and we do not have a policy
of updating or revising, these forward-looking statements, except as required by applicable law.
CONTACT
Steven Lisi, Chief Executive Officer
AIT Therapeutics, Inc.
Steve@AIT-Pharm.com
Bob Yedid
LifeSci Advisors, LLC
Bob@LifeSciAdvisors.com
(646) 597-6989
