LAUSANNE, Switzerland, March 04, 2019 (GLOBE NEWSWIRE) -- AC Immune SA (NASDAQ: ACIU), a Swiss-based,
clinical-stage biopharmaceutical company with a broad pipeline focused on neurodegenerative diseases, today announced that it will
provide oral presentations addressing the progress of four of its early-stage product candidates and diagnostics at the
14th International Conference on Alzheimer’s and Parkinson’s Disease (AD/PD), taking place March
26th-31st in Lisbon.
The four oral presentations by AC Immune and its collaborators at AD/PD will focus on AC Immune’s partnered and
wholly-owned product candidates and technology platform. These presentations will showcase the acceleration and diversification of
its early-stage pipeline; specifically, its alpha-synuclein and Tau PET imaging agents as well as preclinical data on compounds
targeting Tau aggregation and TDP-43 proteinopathies.
Prof. Andrea Pfeifer, Ph.D., CEO of AC Immune SA, commented: "We appreciate the opportunity to
demonstrate the depth of the AC Immune pipeline to the scientific community at AD/PD. These programs highlight the importance of
diagnosing and characterizing neurodegenerative diseases earlier. The findings show that our research capabilities have the
potential to identify new ways to fight neurodegenerative diseases. We believe the field is moving toward combination therapy
and advancing potential therapeutics like these increases the opportunities to evaluate novel, multi-targeted product
candidates.”
Scientific updates at the International Conference on AD/PD conference, Lisbon, Portugal, March 26-31,
2019
Alpha-synuclein PET imaging agent
Identification and characterization of selective and high affinity small molecules for positron emission tomography
(PET) imaging of pathological alpha-synuclein
Date: March 29, 2019 | 8.45 – 9.00 am WET
Location: Auditorium III+IV
Presenter: Oral presentation by F. Capotosti
Tau PET imaging agent
Determination of the optimal scanning time for the assessment of Tau deposition in Alzheimer’s disease using
PI-2620 PET
Date: March 29, 2019 | 8.30 – 8.45 am WET
Location: Auditorium III+IV
Presenter: Oral presentation by A. Stephens
Compounds targeting Tau aggregation
Small molecules targeting Tau propagation demonstrate efficacy in an aggressive tauopathy mouse model
Date: March 31, 2019 | 11.00 – 11.15 am WET
Location: Auditorium II
Presenter: Oral presentation by S. Poli
Anti-TDP-43 antibodies
Discovery and development of diagnostics and therapeutics for TDP-43 proteinopathies
Date: March 31, 2019 | 11.45 am – 12.00 pm WET
Location: Auditorium II
Presenter: Oral presentation by T. Afroz
About AC Immune SA
AC Immune SA is a Nasdaq-listed clinical-stage biopharmaceutical company, which aims to become a global leader in precision
medicine for Neurodegenerative Diseases. The Company designs, discovers and develops therapeutic as well as diagnostic products
intended to prevent and modify diseases caused by misfolding proteins. AC Immune's two proprietary technology platforms create
antibodies, small molecules and vaccines designed to address a broad spectrum of neurodegenerative indications, such as Alzheimer's
disease (AD). The Company's pipeline features nine therapeutic and three diagnostic product candidates, with five currently in
clinical trials. It has collaborations with major pharmaceutical companies including Roche/Genentech, Lilly, Biogen, Janssen
Pharmaceuticals, Nestlé Institute of Health Sciences, Life Molecular Imaging (formerly Piramal Imaging) and Essex
Bio-Technology.
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Forward looking statements
This press release contains statements that constitute “forward-looking statements” within the meaning of
Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements are
statements other than historical fact and may include statements that address future operating, financial or business performance
or AC Immune’s strategies or expectations. In some cases, you can identify these statements by forward-looking words such as “may,”
“might,” “will,” “should,” “expects,” “plans,” “anticipates,” “believes,” “estimates,” “predicts,” “projects,” “potential,”
“outlook” or “continue,” and other comparable terminology. Forward-looking statements are based on management’s current
expectations and beliefs and involve significant risks and uncertainties that could cause actual results, developments and business
decisions to differ materially from those contemplated by these statements. These risks and uncertainties include those described
under the captions “Item 3. Key Information – Risk Factors” and “Item 5. Operating and Financial Review and Prospects” in AC
Immune’s Annual Report on Form 20-F and other filings with the Securities and Exchange Commission. Forward-looking statements speak
only as of the date they are made, and AC Immune does not undertake any obligation to update them in light of new information,
future developments or otherwise, except as may be required under applicable law. All forward-looking statements are qualified in
their entirety by this cautionary statement.
