Stocks were in the red Monday despite encouraging comments on Johnson & Johnson's vaccine from Dr. Anthony Fauci. Bitcoin also declined over the weekend.
The Dow Jones Industrial Average fell 176 points, or 0.5%, while the S&P 500 declined 0.6%, and the Nasdaq Composite dropped 1.2%.
Over the weekend, Fauci said Johnson & Johnson's (JNJ) vaccine could be ready to resume use on Friday following the Food and Drug Administration's pause due to rare blood clots.
Coca-Cola (KO) - Get Report posted stronger-than-expected first-quarter earnings but noted that sales from stadiums, restaurants and movie theaters continued to be pressured by coronavirus closures.
GameStop (GME) shares rose 9.1% after CEO George Sherman said he would step down in July.
Harley-Davidson (HOG) shares were up 10.9% after the company reported a profit of $1.68 a share on sales of $1.4 billion, topping estimates for earnings of 90 cents a share on revenue of $1.3 billion.
Textron (TXT) shares were rising 0.7% after Credit Suisse upgraded the stock to Outperform from Neutral.
Bitcoin dropped 15% on Sunday, the most since February.
Oil prices dipped 15 cents to $62.98 U.S. a barrel.
Gold prices gained 90 cents to $1,781.10 U.S.
The yield on the 10-year U.S. Treasury rose Monday to 1.583%.